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Education:
- 2003-2006. PhD in Biology, University of Santiago de Compostela (USC), Spain.
- 2002-2003. Specialist course in vaccines at USC (25 ECTS).
- 2001-2003. Master in Prevention of Lab Risks at USC (80 ECTS).
- 2000-2002. Advanced Studies Diploma (DEA) in Microbiology at USC.
- 2000-2006. Attendance to a variety of minor courses in Microbiology (x4), informatics (x4) and other technical subjects (x3). 2 specialist courses in applied psychology and working risks (10 ECTS/each) at USC.
- 1995-2000. Degree “Licenciatura” in Biology. (USC), Spain.
Positions:
- 2019-now. Assistant Professor. University of Zaragoza (UZ), Spain.
- 2017-2019. Project Leader. Wageningen University Research (WUR), The Netherlands.
- 2007-2019. Contracted Doctor. Utrecht University (UU), The Netherlands.
- 2006-2007. Post-doctoral Fellow. Netherlands Vaccine Institute, The Netherlands.
- 2003-2006. PhD student, USC.
Research production:
- 30 Publications.
- 24 research in peer-review scientific in journals such as Trends in Microbiology (IF 11,5), PlosPathogens (IF 8,9), Journal Proteome Research (IF 6,9), Environmental Microbiology (IF 6,2), Virulence (IP 5.5), Molecular Microbiology (IF 5.2), among others. Main author of 17 (14 as first author and 3 as the last author). 15 publications in Q1, of which 6 in D1 (first author of 4, second author of 1). 7 publications in Q2. Corresponding author of 12 publications.
- 6 book chapters, single author of 2.
- Inventor of 1 international patent for human vaccines. Ref. 17160604.9
- 36 National and/or International Conference Communications. The first author of 24, 10 presentations as a speaker, last author of 4. 1 communication awarded as Best scientific contribution being first author.
- 3 personal competitive grants for research from the Spanish government, involving DEA, PhD and Postdoc.
- Participation in 10 Funded Research Projects/contracts. 5 projects funded by international companies / institutions and 5 projects by official competitive grant agencies. Remarkably, work Package Leader (WP4), Lead beneficiary and member of Project Management team of the European Project PIGSs (H2020-RUR-2016-1, assigned Budget: €799.000, Total Budget: € 4.998.103), among others.
- 2 6-years research trajectory (Goberment of Aragón)
Other merits:
- Personal invitations to scientific seminars (x6).
- Supervision of 30 Research projects to National/ International Bachelor (or grado / licenciatura) students (x13), Master students (x12), Fellow researchers / postdocs (x5), and technical students (x2). Research projects involved from 16 ECTS to 60 ECTS. 1 TFG.
- Reviewer for scientific journals (x18) (56 reviews) such as PlosOne (x12), Proteomics (x1), BMC Microbiology (x9), ScienceReports (x1), among others. All upon invitation.
- Dissemination activities for Newspapers and interviews (x5)
- Member of Assessment Committee for research Projects (IberCaja, x2) and external reviewer for PhD (Universidad da Coruna, x1).
- Contribution to organization of 1 congress for the Spanish Society of Microbiology.
Teaching Activities :
- 2019/2020 Participation in 4 Innovation Docent Projects at UZ, being the coordinator of one.
- 2003-2020. Lectures (606 h) and practical courses (580 h) to BsC and MsC students in different Universities USC, UU and UZ in official courses related to Microbiology, Immunology and Biotechnology. - Author /co-author of 24 research papers in pre-revised journals. 524 citations, H index: 13, i10 index: 18 (source: Google Scholar)
- The main author of 17 publications. The first author of 14 publications, last author of 3 publications, second author of 3.
- 19 publications with or less than 6 co-authors, two publications with 1 coauthor and 1 single-author publication.
- Impact factors ranging 11 – 2. 15 publications in Q1 (first author of 8, second author of 2, last author of 3) of which 6 publications in D1 (first author of 4, second author of 1, and 6th author of 1). 7 publications in Q2.
- 6 book chapters, being the first author of 2.
Journal articles
- Uruén, Cristina; Fernandez, Ana; Arnal, José Luis; del Pozo, Mateo; Amoribieta, Maria Casas; de Blas, Ignacio; Jurado, Paula; Calvo, Jorge Hugo; Gottschalk, Marcelo; González-Vázquez, Luis Daniel; Arenas, Miguel; Marín, Clara M.; Arenas, Jesús. Genomic and phenotypic analysis of invasive Streptococcus suis isolated in Spain reveals genetic diversification and associated virulence traits. VETERINARY RESEARCH. 2024. DOI: 10.1186/s13567-024-01267-0
- Arenas, Jesús. Editorial: Pathogenic Neisseria: Pathogenicity, vaccines, and antibiotic resistance. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2023. DOI: 10.3389/fcimb.2022.1119244
- Jurado, Paula; Uruén, Cristina; Martínez, Sara; Lain, Elena; Sánchez, Sandra; Rezusta, Antonio; López, Víctor; Arenas, Jesús. Essential oils of Pinus sylvestris, Citrus limon and Origanum vulgare exhibit high bactericidal and anti-biofilm activities against Neisseria gonorrhoeae and Streptococcus suis. BIOMEDICINE & PHARMACOTHERAPY. 2023. DOI: 10.1016/j.biopha.2023.115703
- Uruén, Cristina; Gimeno, Jorge; Sanz, Marina; Fraile, Lorenzo; Marín, Clara M.; Arenas, Jesús. Invasive Streptococcus suis isolated in Spain contain a highly promiscuous and dynamic resistome. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2023. DOI: 10.3389/fcimb.2023.1329632
- Mohapatra, Harapriya; Arenas, Jesús. Editorial: Novel insights on the role of bacterial membrane proteins in virulence and pathogenesis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2023. DOI: 10.3389/fcimb.2023.1282672
- Olivan-Muro, Irene; Sarasa-Buisan, Cristina; Guio, Jorge; Arenas, Jesús; Sevilla, Emma; Fillat, Maria F. Unbalancing Zur (FurB)-mediated homeostasis in Anabaena sp. PCC7120: Consequences on metal trafficking, heterocyst development and biofilm formation. ENVIRONMENTAL MICROBIOLOGY. 2023. DOI: 10.1111/1462-2920.16434
- Dresen, Muriel; Schaaf, Desirée; Arenas, Jesús; de Greeff, Astrid; Valentin-Weigand, Peter; Nerlich, Andreas. Streptococcus suis TrpX is part of a tryptophan uptake system, and its expression is regulated by a T-box regulatory element. SCIENTIFIC REPORTS (NATURE PUBLISHING GROUP). 2022. DOI: 10.1038/s41598-022-18227-3
- Uruén, Cristina; García, Carla; Fraile, Lorenzo; Tommassen, Jan; Arenas, Jesús. How Streptococcus suis escapes antibiotic treatments. VETERINARY RESEARCH. 2022. DOI: 10.1186/s13567-022-01111-3
- Uruén, C.; Chopo-Escuin, G.; Tommassen, J.; Mainar-Jaime, R.C.; Arenas, J. Biofilms as promoters of bacterial antibiotic resistance and tolerance. ANTIBIOTICS. 2021. DOI: 10.3390/antibiotics10010003
- del Amparo R.; Branco C.; Arenas J.; Vicens A.; Arenas M. Analysis of selection in protein-coding sequences accounting for common biases. BRIEFINGS IN BIOINFORMATICS. 2021. DOI: 10.1093/bib/bbaa431
- Dresen, M.; Rohde, M.; Arenas, J.; Greeff, A. De; Nerlich, A.; Valentin-Weigand, P. Identification and characterization of the cell division protein MapZ from Streptococcus suis. MICROBIOLOGYOPEN. 2021. DOI: 10.1002/mbo3.1234
- Arenas, Jesús; Szabo, Zalan; Wal, Jelle Van Der; Maas, Coen; Riaz, Tahira; Tonjum, Tone; Tommassen, Jan. Serum proteases prevent bacterial biofilm formation: role of kallikrein and plasmin. VIRULENCE. 2021. DOI: 10.1080/21505594.2021.2003115
- Arenas, J.; Catón, L.; Van Den Hoeven, T.; de Maat, V.; Cruz Herrero, J.; Tommassen, J. The outer-membrane protein MafA of Neisseria meningitidis constitutes a novel protein secretion pathway specific for the fratricide protein MafB. VIRULENCE. 2020. DOI: 10.1080/21505594.2020.1851940
- Arenas, J.; Zomer, A.; Harders-Westerveen, J.; Bootsma, H.J.; de Jonge, M.I.; Stockhofe-Zurwieden, N.; Smith, H.E.; de Greeff, A. Identification of conditionally essential genes for Streptococcus suis infection in pigs. VIRULENCE. 2020. DOI: 10.1080/21505594.2020.1764173
- Wrobel, A.; Saragliadis, A.; Pérez-Ortega, J.; Sittman, C.; Göttig, S.; Liskiewicz, K.; Spence, M.H.; Schneider, K.; Leo, J.C.; Arenas, J.; Linke, D. The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence. ENVIRONMENTAL MICROBIOLOGY. 2020. DOI: 10.1111/1462-2920.15051
- Arenas, J.; Pupo, E.; Phielix, C.; David, D.; Zariri, A.; Zamyatina, A.; Tommassen, J.; Van Der Ley, P. Shortening the lipid A acyl chains of Bordetella pertussis enables depletion of lipopolysaccharide endotoxic activity. VACCINES. 2020. DOI: 10.3390/vaccines8040594
- Arenas, Jesús; Bossers-de Vries, R.; Harders-Westerveen, José; Buys, Herma; Ruuls-Van Stalle, Lisette; Stockhofe-Zurwieden, Norbert; Zaccaria, Edoardo; Tommassen, Jan; Wells, Jerry M.; Smith, Hilde E.; de Greef, Astrid. In vivo transcriptomes of Streptococcus suis reveal genes required for niche-specific adaptation and pathogenesis. VIRULENCE. 2019. DOI: 10.1080/21505594.2019.1599669
- Arenas, Jesús; Pupo, Elder; de Jonge, Eline; Pérez-Ortega, Jesús; Schaarschmidt, Joerg; Van Der Ley, Peter; Tommassen, Jan. Substrate specificity of the pyrophosphohydrolase LpxH determines the asymmetry of Bordetella pertussis lipid A. JOURNAL OF BIOLOGICAL CHEMISTRY. 2019. DOI: 10.1074/jbc.RA118.004680
- Van Boxtel, Ria; Wattel, Agnes A.; Arenas, Jesús; Goessens Wil H.; Tommassen, Jan. Acquisition of Carbapenem Resistance by Plasmid-Encoded-AmpC-Expressing Escherichia coli. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2017. DOI: 10.1128/AAC.01413-16
- Tommassen, Jan; Arenas, Jesús. Biological functions of the secretome of Neisseria meningitidis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2017. DOI: 10.3389/fcimb.2017.00256
- Pérez-Ortega, Jesús; Rodríguez, Antonio; Ribes, Eduardo; Tommassen, Jan; Arenas, Jesús. Interstrain Cooperation in Meningococcal Biofilms: Role of Autotransporters NalP and AutA. FRONTIERS IN MICROBIOLOGY. 2017. DOI: 10.3389/fmicb.2017.00434
- Arenas, Jesús; Tommassen, Jan. Meningococcal Biofilm Formation: Let´s stick together. TRENDS IN MICROBIOLOGY. 2017. DOI: 10.1016/j.tim.2016.09.005
- Arenas, Jesús; Paganelli, Fernanda; Rodriguez Castaño, Patricia; Cano-Crespo, Sara; Van Der Ende, Arie; Van Putten, Jos; Tommassen, Jan. Expression of the Gene for Autotransporter AutB of Neisseria meningitidis Affects Biofilm Formation and Epithelial Transmigration. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2016. DOI: 10.3389/fcimb.2016.00162
- Arenas, Jesús; de Maat, Vincent; Catón, Laura; Krekorian, Massis; Cruz Herrero, Juan; Ferrera, Flavio; Tommassen, Jan. Fratricide activity of MafB protein of N. meningitidis strain B16B6. BMC MICROBIOLOGY. 2015. DOI: 10.1186/s12866-015-0493-6
- Roussel-Jazedé, Virginie; Arenas, Jesús; Langereis, Jd.; Tommassen, Jan; Van Ulsen, Peter. Variable processing of the IgA protease autotransporter at the cell surface of Neisseria meningitidis. MICROBIOLOGY (UNITED KINGDOM). 2014. DOI: 10.1099/mic.0.082511-0
- Ur Rahman, S.; Arenas, Jesús; Ozturk Dekker, N.; Van Ulsen, Peter. The polypeptide transport-associated (POTRA) domains of TpsB transporters determine the system specificity of two-partner secretion systems. JOURNAL OF BIOLOGICAL CHEMISTRY. 2014. DOI: 10.1074/jbc.M113.544627
- Arenas, Jesús; Cano, Sara; Nijland, Reindert; Van Dongen, Vééne; Rutten, Lucy; Van Der Ende, Arie; Tommassen, Jan. The meningococcal autotransporter AutA is implicated in autoaggregation and biofilm formation. ENVIRONMENTAL MICROBIOLOGY. 2014. DOI: 10.1111/1462-2920.12581
- Arenas, Jesús; Schipper, Kim; Van Ulsen, Peter; Van Ende, Arie; Tommassen, Jan. Domain exchange at the 3’ end of the gene encoding the fratricide meningococcal two-partner secretion protein A. BMC GENOMICS. 2013
- Grijpstra, Jan; Arenas, Jesús; Rutten, Lucy; Tommassen, Jan. Autotransporter secretion: varying on a theme. RESEARCH IN MICROBIOLOGY. 2013. DOI: 10.1016/j.resmic.2013.03.010
- Arenas, Jesús; Nijland, Reindert; Rodriguez, Francisco Javier; Bosma, Tom; Tommassen, Jan. Involvement of three meningococcal surface-exposed proteins, the heparin-binding protein NhbA, the a-peptide of IgA protease and the autotransporter protease NalP, in initiation of biofilm formation. MOLECULAR MICROBIOLOGY. 2013. DOI: 10.1111/mmi.12097
- Arenas, Jesús The role of bacterial lipopolysaccharides as immunomodulator in vaccine and drug development. ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS. 2012. DOI: 10.2174/187153012802002884
- Arenas, Jesús; Van Dijhen, Harry; Kuipers, Besty; Hamstra, Jan; Tommassen, Jan; Van Der Ley, Peter Coincorporation of LpxL1 and PagL mutant lipopolysaccharides into liposomes with Neisseria meningitidis Opacity protein: Influence on endotoxic and adjuvant activity. CLINICAL AND VACCINE IMMUNOLOGY. 2010. DOI: 10.1128/CVI.00423-09
- Van Vliet, Sandra J.; Steeghs, Liana; Bruijns, Sven Cm.; Vaezirad, Mm.; Snijders Blok, C.; Arenas Busto, Jesús A.; Deken, M.; Van Putten, Jmc.; Van Kooyk, Y. Variation of Neisseria gonorrhoeae lipooligosaccharide directs dendritic cell induced T helper responses. PLOS PATHOGENS. 2009. DOI: 10.1371/journal.ppat.1000625
- Arenas, Jesús; Abel, Ana; Sánchez, Sandra; Marzoa, Juan; Berrón, Sandra; Van Der Ley, Peter; Criado, María Teresa; Ferreirós, Carlos M. A cross-reactive neisserial antigen encoded by the NMB0035 locus shows high sequence conservation but variable surface accessibility. JOURNAL OF MEDICAL MICROBIOLOGY. 2008. DOI: 10.1099/jmm.0.47172-0
- Abel, Ana; Sánchez, Sandra; Arenas, Jesús; Criado, María Teresa; Ferreirós, Carlos. Bioinformatic analysis of outer membrane proteome of Neisseria meningitidis and Neisseria lactamic. INTERNATIONAL MICROBIOLOGY. 2007. DOI: 10.2436/20.1501.01.2
- Arenas, Jesús; Abel, Ana; Sánchez, Sandra; Alcalá, Belén; Criado, Teresa; Ferreirós, Carlos. NMB0035 codes for a 47 kDa surface-accessible antigen highly conserved in Neisseria meningitidis and commensal Neisseria. INTERNATIONAL MICROBIOLOGY. 2006
- Sánchez, Sandra; Abel, Ana; Arenas, Jesús; Criado, María Teresa; Ferreirós, Carlos. Cross-linking analysis of high-molecular-weight outer membrane complexes of Neisseria meningitidis. RESEARCH IN MICROBIOLOGY. 2006. DOI: 10.1016/j.resmic.2005.06.011
- Sánchez, Sandra; Arenas, Jesús; Abel, Ana; Criado, María Teresa; Ferreirós, Carlos. Analysis of outer membrane protein complexes and heat-modifiable proteins in Neisseria strains using two-dimensional diagonal electrophoresis. JOURNAL OF PROTEOME RESEARCH. 2005. DOI: 10.1021/pr049846i
Books
- Caracterización molecular y genética de la proteína P47 de "neisseria meningitidis" : una alternativa para el desarrollo de una vacuna antimeningocócica universal Arenas Busto, Jesús Andrés. 2006
Scientific chapters
- Y. ruckeri NVH_3758 inverse autotransporters contribute to biofilm formation. ; ; ; ; ; ; STRUCTURAL AND FUNCTIONAL STUDIES OF THE YERSINIA RUCKERI INVERSE AUTOTRANSPORTERS. 2019
- Bacterial Lipopolysaccharides. Arenas Busto, Jesús Andrés. COMPENDIUM OF INFLAMMATORY DISEASES. 2016
- Bacterial lipopolysaccharide as adjuvants. Arenas Busto, Jesús Andrés. MOLECULAR VACCINES -FROM PROPHYLAXIS TO THERAPY. 2014
- Outer-membrane-embedded and associated proteins and their role in adhesion and pathogenesis. Van Dam, V.; Roussel-Jazédé, V.; Arenas, J.A.; Bos, M.; Tommassen, J. BACTERIAL MEMBRANES. STRUCTURAL AND MOLECULAR BIOLOGY. 2014
- The Two Partner Secretion transporter TpsB2 of Neisseria meningitidis secretes a non-cognate full-length TpsA1 but not to full functionality. ur Rahman S; Jesús Arenas; Ozturk; dekker N; Peter van Ulsen. SPECIFICITY OF THE TWO PARTNER SECRETION SYSTEM. 2014
- Variable processing of the serine-protease autotransporters of Neisseria meningitidis. Biogenesis and functions of neisserial autotransporters. Virginie Roussel-Jazédé; Jesús Arenas; Ma L; van Baarle S; Langereis JD; Jan Tommassen; Peter van Ulsen. BIOGENESIS AND FUNCTIONS OF NEISSERIAL AUTOTRANSPORTERS. 2011
Projects
- PID2023-146823OB-I00: Métodos Innovativos para prevenir y controlar la infección y transmisión de Streptococcus suis a través de estrategias vacunales. 01/09/24 - 31/12/28
- LMP58_21: Análisis de la Transferencia de Resistencias a Antibióticos desde Streptococcus suis a otros Patógenos de Humanos y Evaluación de Alternativas Innovadoras para su Prevención (TRANSIT). 18/09/21 - 30/09/23
- PID2020-114617RB-I00: Evaluación del potencial vacunal de receptores ABC para generar nuevas vacunas contra Streptococcus suis (ABC-VACINESs). 01/09/21 - 31/08/25
- UZ2020-BIO-01: Multi-estudio de aislados de Streptococcus suis en España (Multi-Strepts). 01/10/20 - 30/03/22
- Engineering fluorescent Streptococcus suis (fSs, ref 1600001704). 01/03/18 - 31/12/18
- Program for Innovative Global prevention of Streptococcus suis. 01/04/17 - 01/07/22
- A technology Center for Bacterial vaccines (Bac-Vactory). 01/01/17 - 01/05/21
- Role of Neisseria secretome during infection and protection. 01/01/06 - 31/12/11
- Complexos proteicos de alto peso molecular da membrana externa dos meningococos: estructura, antexinicidade, accesibilidade e idoneidade para o desenvolvemento de novas vaccinas. 01/01/05 - 01/01/09
Contracts
- ANÁLISIS DE LA ACTIVIDAD BACTERICIDA Y ANTI-BIOFILM DE COMPUESTOS SINTÉTICOS CONTRA STREPTOCOCCUS SUIS. 26/03/24 - 26/12/24
- CESIÓN DEL USO DE VÍDEOS DIDÁCTICOS. 15/06/23 - 15/06/27
- CERTIFICACIÓN DE PROYECTOS DE I+D+I. 01/05/23 - 31/12/23
- ESTUDIOS EN MICROBIOLOGIA. 01/01/23 - 31/12/23
- ESTUDIOS EN MICROBIOLOGIA. 01/09/21 - 31/12/21
- DETECCION DE SALMONELLA, CRIPTOSPORIDIUM SPP. Y E. COLI PATOGENOS EN MUESTRAS FECALES DE PALOMAS CAPTURADAS EN LA CIUDAD DE ZARAGOZA. 15/03/21 - 15/09/21
- CERTIFICACIÓN DE PROYECTOS DE I+D+I. 01/02/21 - 31/12/21
- Evaluación del Efecto Bactericida de Extractos Naturales sobre Streptococcus suis. 01/10/20 - 30/04/21
- ENGENIEER LESS REACTOGENIC BORDETELLA PERTUSSIS STRAINS. 01/01/14 - 31/12/15
- Elucidating the secretion of new proteins. 01/01/12 - 31/03/13
- Innate Immune Receptors. 01/01/05 - 31/12/08
- Vaccine development against Neisseria meningitidis. 01/01/00 - 31/12/11
Supervision of undergraduate dissertations
- Identificación de genes de resistencia a antibióticos en bacterias patógenas de animales y sus mecanismos de traspaso a humanos. Universidad de Zaragoza. Notable. 17/07/24
- Análisis de la función biológica de un posible transportador de aminoácidos en Streptococcus suis. Universidad de Zaragoza. Sobresaliente. 17/07/24
- Estudio de la actividad antibacteriana de compuestos naturales contra Strepcococcus suis. Universidad de Zaragoza. Sobresaliente. 21/12/23
- Estudio de un posible transportador de glutamina en Streptococcus suis. Universidad de Zaragoza. Notable. 13/12/23
- Análisis de la respuesta inmune innata de cerdos contra antígenos subcapsulares de Streptococcus suis. Universidad de Zaragoza. Notable. 13/12/23
- Análisis de la resistencia a antibióticos en el patógeno porcino Streptococcus suis. Universidad de Zaragoza. Matrícula de honor. 22/09/23
- Formación de biofilms por Streptococcus suis. Universidad de Zaragoza. Sobresaliente. 19/12/22
- Análisis del potencial de extractos derivados de plantas cultivadas en aragón para inactivar bacteria multiresistente. Universidad de Zaragoza. Notable. 13/10/22
- Análisis de extractos naturales comerciales como alternativa contra Streptococcus suis. Universidad de Zaragoza. Matrícula de honor. 13/10/22
- Capacidad anti-biofilm de superficies de cerámica desarrolladas mediante métodos mecanizados. Universidad de Zaragoza. Notable. 07/10/21
- Estudio de la actividad bactericida and anti-biofilm de aceites esenciales en Neisseria gonorrhoeae. Universidad de Zaragoza. Sobresaliente. 06/10/21
- Estudios sobre el control transcripcional de la expresión de genes mediada por hierro en Clostridium difficile. Universidad de Zaragoza. Sobresaliente. 23/09/21
- Eficacia antimicrobiana de aceites esenciales. Universidad de Zaragoza. Sobresaliente. 01/12/20
- Biofilms en la industria alimentaria. Universidad de Zaragoza. Notable. 01/12/20
- El papel de los biofilms en la resistencia a los antibióticos. Universidad de Zaragoza. Sobresaliente. 08/09/20
- Identificación de resistencias frente a antibióticos Beta-lactámicos en Salmonella enterica aislada de ganado porcino en Aragón. Universidad de Zaragoza. Matrícula de honor. 13/12/19
Supervision of master's theses
- Estudio de mecanismos de resistencia de Streptococcus suis a antibióticos β-lactámicos. Universidad de Zaragoza. Matrícula de honor. 16/12/24
- Estrategías para la formación de biofilms en Streptococcus suis y su impacto en la tolerancia a antibioticos. Universidad de Zaragoza. Matrícula de honor. 05/07/24
- Estudio de extractos naturales como alternativa a antibióticos contra bacterias patógenas. Universidad de Zaragoza. Sobresaliente. 21/12/23
- Resistencia a antibioticos de Streptococcus suis patogenos aislados en España. Universidad de Zaragoza. Notable. 22/12/22
- Estudios de actividad funcional de extractos naturales contra Neisseria gonorrhoeae. Universidad de Zaragoza. Matrícula de honor. 22/12/22
- Análisis de candidatos vacunales contra Streptococcus suis. Universidad de Zaragoza. Matrícula de honor. 19/12/22
- Caracterización y genotipado de cepas invasivas de Streptococcus suis aisladas en Cataluña. Universidad de Zaragoza. Sobresaliente. 21/12/21
Other work supervisions
- Biofilm formation strategies of Streptococcus suis. Wageningen Research University and LST. 8. 15/06/18. Major Research Project (5 months)
- Identification of novel factors involved in Streptococcus suis porcine macrhophage interactions. University of Wageningen and LST. 7.8. 12/06/19. Final Research Project - 6 month
- Involvement of surface exposed structures of Streptococcus suis in biofilm formation. Wageningen University and Research. 7.5. 27/06/19. Major Research Project (5 months)
- Purification of meningococcal recombinant proteins in Escherichia coli. Utrecht University. 8.35. 09/09/15. Major Research Project for Bachelor (Licenciado) student in Pharmacy from University of Málaga (51 ECTS)
- Modification of LipidA in Bordetella pertussis. Utrecht University. 7.5. 14/09/16. Major Research Project for Master Student in Biomedical Sciences from University of Amsterdam (48 ECTS)
- Characterization of MafA/MafB system in Neisseria meningitidis. Utrecht University. 8. 24/11/11. Major Research Project for Master Student in Molecular Sciences from Utrecht University (51 ECTS)
- Implication of the autotransporter AutB in biofilm formation. Utrecht University. 6.2. 16/11/16. Major Research Project for Master student in Molecular and Cellular Life Sciences from University of Utrecht (51 ECTS)
- Role of C-terminal part of meningococcal MafB proteins and potential immunity proteins. Utrecht University. 7.35. 11/03/15. Major Research Project for Master student in Molecular and Cellular Life Sciences (University of Utrecht) (51 ECTS)
- Secretion and Processing of meningococcal MafB proteins. Utrecht University. 8. 16/09/15. Major Research Project for Master student in Techniques and Quality of Water (University of Granada) (51 ECTS)
- Translocation and functional activities of MafA proteins. Utrecht University. 8.25. 29/08/14. Major Research project for Master Student in Molecular and Life Sciencies (45 ECTS)
- What is the role of meningococcal autotransporters AutA and AutB during infection?. Utrecht University. 7. 14/01/14. Major research project for Master Student in Science and Business Management from Utrecht University studies (42 ECTS)
- Engineering Fluorescent Neisseria. Utrecht University. 5. 24/10/13. Minor Research Project for Bachelor Student in Biology (licenciado) from University of Málaga (15 ECTS)
- Implication of the NalP protease on biofilm formation of Neisseria meningitidis I. Utrecht University. 8. 30/01/11. Minor Research Project for Bachelor Student in Biology (licenciado) from University of Málaga (16 ECTS)
- Implication of the NalP protease on biofilm formation of Neisseria meningitidis II. Utrecht University. 7. 30/01/11. Minor research Project for Bachelor Student in Biology from University of Málaga (16 ECTS)
- Analysis of expression of meningococcal autotransporters AutA and AutB. Utrecht University. 8. 11/06/12. Research Project for Bachelor in Biology from University of Málaga (33 ECTS)
- Characterization of toxic anti-toxic elements in Neisseria meningitidis. Utrecht University. 7.5. 31/03/14. Research Project for Bachelor in Life Sciences from University of Milan (42 ECTS)
- Increased Bacterial Interactions does not enhance intra-bacterial competition. Utrecht University. 7.5. 01/12/15. Research Project for Bachelor student in Biology (University of Utrecht) (7.5 ECTS)
- Purification and folding of recombinant meningococcal autotransporteres in E coli for structural analysis. Utrecht University. 7.5. 16/11/16. Major Research Project for Master Student in Molecular and Cellular Life Sciences (University of Utrecht)
- Cloning and expression of Maf proteins of Neisseria in E coli. Utrecht University. N/A. 30/09/15. Postdoc Researcher fellow (guest) from University of Zaragoza (3 months)
- Cloning strategies in the Maf system. Utrecht University. N/A. 31/08/15. Research Project for Fellow Researcher (Guest) from University of Zaragoza (3 months)
- Novel Secretion systems in Gram negative bacteria. Utrecht University. N/A. 30/09/16. Research Project for Fellow Researcher (Guest) from University of Zaragoza (6 months)
- Preparation of mutants in LPS biosynthesis route of Bordetella pertussis. Utrecht University. N/A. 31/12/15. Research Project for Fellow-researcher (Guest from University of Zaragoza) - 3 months
- Analysis of the specificity of the flipasse MsbA. Utrecht University. N/A. 30/03/16. Research Project for Fellow-researcher (Guest from University of Zaragoza) - 6 months
- Biofilm formation of Neisseria meningitidis during interaction with eukariotic cells. Utrecht University. 5. 19/10/16. Research project for Bachelor Student (Licenciado) in Pharmacy from University of Málaga (60 ECTS)
- Bacterial interactions within Neisseria species and meningococcal strains. Utrecht University. 7.5. 25/04/17. Research project for Master Student in Research and Advances in Microbiology from University of Málaga (51 ECTS)
- Protein interactions in a novel secretion system in Neisseria meningitidis. Utrecht University. 7.75. 21/09/15. Major Research Project (51 ECTS)
- Characterization of the meningococcal autotransporter AutB. Utrecht University. 7. 01/06/15. Major Research Project (51 ECTS)
- The meningococcal proteins NhbA, IgAp and AutA are involved in intra and inter bacterial interactions during biofilm formation. Utrecht university. 8. 23/10/15. Research Project for Master Student in Research and Advances in Microbiology from University of Granada (51 ECTS)
- Analysis of new secretion systems for secretion of heterologous proteins in Escherichia coli. Utrecht University. 7.1. 29/07/16. Research project for Master Student in Biotechnology from University of Vigo (60 ECTS)
Patents
- 17160604.9. Bordetella vaccines comprising LPS with reduced reactogenicity. Peter van der Ley; Jesús Arenas, Elder Pupo, Jan Tommassen 2017
Previous research
- Project Leader. University of Wageningen. 01/05/17 - 15/02/19
- Guest Researcher and Lecture. Utrecht University. 01/05/17 - 15/01/19
- Researcher and Teacher (Contracted). Utrecht University. 01/01/08 - 31/05/17
- Post-doctoral Researcher (Contracted). Utrecht University. 01/10/07 - 30/12/07
- Post-doctoral Fellow. The Netherlands Vaccine Institute / RIVM. 01/10/06 - 30/09/07
- Researcher (PhD student). Universidad de Santiago de Compostela. 01/02/03 - 31/05/06
- Researcher (Master student). Universidad de Santiago de Compostela. 01/09/00 - 31/12/02
Participation in conferences
- 12th European Workshop on the Biology of Cyanobacteria. Participativo - Póster. Metalloregulator Zur / FurB of cyanobacterium Anabaena sp. PCC7120 goes beyond zinc homeostasis regulation: impact on metal trafficking, biofilm formation and heterocyst development. Sevilla. 03/09/24
- 45th Congress of the Spanish Society of Biochemistry and Molecular Biology. Participativo - Ponencia oral (comunicación oral). Beyond zinc homeostasis: the link between metalloregulator Zur / FurB of cyanobacteria Anabaena sp. PCC7120 and metal trafficking, biofilm formation and heterocyst development. Zaragoza. 05/09/23
- X National Conference BIFI 2021. Participativo - Póster. Unraveling biofilm formation in the filamentous cyanobacterium Anabaenasp. PCC7120. Zaragoza. 03/02/21
- USATIC2020. Participativo - Otros. MEJORA DE LA DOCENCIA PRÁCTICA A TRAVÉS DE MINIPROYECTOS DE INVESTIGACIÓN DIRIGIDOS EN COMBINACIÓN CON TICS. ZARAGOZA. 08/07/20
- USATIC2020. Participativo - Otros. ENSEÑAR PREGUNTANDO: INCORPORACIÓN DE CUESTIONARIOS EN CLASE CON MOODLE. ZARAGOZA. 08/07/20
- 12 th International symposium on bordetella. Participativo - Otros. LIPID A ENGINEERING IN BORDETELLA PERTUSSIS BY ALTERING THE ACYL CHAIN LENGTH ENABLES MODIFICATION OF VACCINE ENDOTOXIC ACTIVITY. Brussels. 09/04/19
- FEMS2015. Participativo - Otros. Expression of the meningococcal autotransporter AutB and its impact on biofilm formation. Mastricht. 08/06/15
- FEMS2015. Participativo - Otros. Analysis of interactions between Neisseria strains in biofilms. Mastricht. 08/06/15
- CHAINS2014. Participativo - Póster. New constructs to generate fluorescent bacteria of Neisseria spp. as a tool to study interbacterial interactions. Vedhoven. 17/11/14
- CHAINS2014. Participativo - Póster. Characteristics of MafA suggest a novel secretion system. Vedhoven. 17/11/14
- CHAINS2014. Participativo - Ponencia oral (comunicación oral). A novel secretion system in Gram negative bacteria; the mafA/B system of Neisseria meningitidis. Vedhoven. 17/11/14
- NWO CV study groups meeting. Participativo - Ponencia oral (comunicación oral). A novel meningococcal autotransporter implicated in autoaggregation and biofilm formation. Vedhoven. 09/12/13
- Secretieplatform Annual Meeting,. Participativo - Ponencia oral (comunicación oral). A novel secretion system in Gram negative bacteria. groningen. 07/03/13
- Scientific meeting NWO-CW study groups protein research, nucleic acids and lipids & biomembranes. Participativo - Póster. The autotransporter NalP, a phase-variable expressed protease, regulates the initiation of meningococcal biofilm formation through eDNA. Veldhoven. 06/12/10
- ALW Platform Molecular Genetics Annual Meeting. Participativo - Ponencia oral (comunicación oral). Intraspecies competition mechanisms in Neisseria meningitidis. Lunteren. 14/10/10
- ALW Platform Molecular Genetics Annual Meeting. Participativo - Ponencia oral (comunicación oral). Biofilm formation in Neisseria meningitidis: Implication of the autotransporter NalP. Lunteren. 14/10/10
- ALW Platform Molecular Genetics Annual Meeting. Participativo - Ponencia oral (comunicación oral). Regulation of biofilm formation in Neisseria meningitidis. Lunteren. 14/10/10
- ALW Platform Molecular Genetics Annual Meeting. Participativo - Ponencia oral (comunicación oral). Gene conversion at the 3' end of the gene for the secreted meningococcal TpsA protein. Lunteren. 14/10/10
- Secretieplatform Annual Meeting. Participativo - Ponencia oral (comunicación oral). The Two-partner Secretion System of Neisseria meningitidis and its role on invasion. Haren. 08/04/10
- Secretieplatform Annual Meeting. Participativo - Ponencia oral (comunicación oral). Role of the meningococcal autotransporter NalP in virulence and its relation to lipoprotein GNA2132. Haren. 08/04/10
- Secretieplatform Annual Meeting. Participativo - Ponencia oral (comunicación oral). Role of Neisserial autotransporters in the interaction with eukaryotic cells. Haren. 08/04/10
- Secretieplatform Annual Meeting. Participativo - Ponencia oral (comunicación oral). Bacterial warfare: The meningococcal Two-Partner-Secretion Protein A is a versatile fratricide molecule. Haren. 08/04/10
- Annual Meeting of NWO-CW study groups. Participativo - Póster. Gene conversion mediates sequence variation at the C terminus of the secreted meningococcal TpsA protein. Veldhoven. 07/12/09
- 16th International Pathogenic Neisseria Conference. Participativo - Póster. Processing of the Two-Partner Secretion A (TpsA) proteins of Neisseria meningitidis by the autotransporter NalP. rotterdam. 07/09/08
- 16th International Pathogenic Neisseria Conference. Participativo - Póster. Coincorporation of LpxL1 and PagL LPS into liposomes with Neisseria Opacity protein: Influence on their adjuvant activity. rotterdam. 07/09/08
- VI Congreso del Grupo de Microbiología Molecular de la Sociedad Española de Microbiología (SEM). Participativo - Póster. NM0035 gen of Neisseria meningitidis codes for an exposure lipoprotein highly antigenic and conserved. Lerida. 13/09/06
- 2nd Congress of Federation of European Microbiological Societies (FEMS. Participativo - Póster. Immunoproteome maps for the location of common antigens of Neisseria meningitidis and Neisseria lactamica. Madrid. 04/07/06
- III Congreso de la Sociedad Española de Vacunología. Participativo - Otros. Evaluation of the utility of the two-dimensional electrophoresis as technique for the identification of common antigens in Neisseria meningitidis and Neisseria lactamica strains. Madrid. 10/11/05
- III Congreso de la Sociedad Española de Vacunología. Participativo - Póster. Evaluation of the utility of the two-dimensional electrophoresis as technique for the identification of common antigens in Neisseria meningitidis and Neisseria lactamica strains. Madrid. 10/11/05
- Congresso da Socidade Iberica de Citomyca. Participativo - Póster. Flow cytometry analysis of the accessibility of a 47 kDa outer membrane antigen of Neisseria meningitidis. O Porto. 05/05/05
- Congresso da Socidade Iberica de Citomyca. Participativo - Póster. Analysis of the correlation of bactericidal activity and surface exposure of a 47Kda lipoprotein of Neisseria meningitidis. O Porto. 05/05/05
- V Congreso del grupo de Microbiología Molecular de la SEM. Participativo - Otros. Comparison of proteome and antigenic maps of outer membrane proteins of Neisseria meningitidis and Neisseria lactamica. Jaca. 07/09/04
- V Congreso del grupo de Microbiología Molecular de la SEM. Participativo - Otros. Accessibility and expression in the surface of Neisseria meningitidis of a protein highly conserved antigenic. Jaca. 07/09/04
- XI Congreso de la SEM. Participativo - Otros. Detection of the meningococcal Class V proteins (Opa) by Diagonal Electrophoresis. Santiago de Compostela. 21/09/03
- 11th International Conference of European Association of Fish Pathologists (EAFP). Participativo - Otros. Evaluation of an enzyme linked immune assay for serological typing of Tenacibaculum maritimum. Malta. 21/09/03
- XXI Congreso de la SEM. Participativo - Otros. Analysis of the associations among proteins of outer membrane of Neisseria meningitidis. XXI Congreso de la SEM. Santiago de Compostela. 21/09/03
- XI Congreso de la SEM. Participativo - Otros. Study of Associations among outer membranes proteins of Neisseria: Cross-Linking with Formaldehyde. Santiago de Compostela. 21/09/03
- X Congreso de la SEM. Participativo - Otros. Identification of Tenacibaculum Maritimum by an Enzymatic Immunoassay. Sevilla. 05/09/02
- III Congreso de Microbiología del Medio Acuático. Participativo - Otros. Identification of Flavobacterium psycrhophilum for ELISA. Santiago de Compostela. 05/02/00
Research stays
- Wageningen BioVeterinary Research. Lelystad. Holanda. 01/05/17 - 15/01/19
- Utrecht University, Faculty of Biology. Utrecht. Holanda. 01/01/08 - 15/01/19
- Utrecht University, faculty of Veterinary. Utrecht. Holanda. 01/10/07 - 31/12/07
- Netherlands Vaccine Institute. Bilthoven. Holanda. 01/10/06 - 30/09/07
- Universidad de Santiago de Compostela. Santiago de Compostela. España. 01/02/03 - 22/06/06
- Universidad de Santiago de Compostela. Santiago de Compostela. España. 01/09/00 - 01/02/03
Committees
- IberCaja-CAI. Universidad de Zaragoza. 01/01/19
- External Reviewer phD. Universidad de Zaragoza. 06/06/18 - 06/06/18
Organization of R&D activities
- Collaborator in the organization of Congreso de la Sociedad Espanhola de Microbiologia. 21/09/03 - 25/09/03
Other merits
- Lecture. 31/05/19
- Lecture (upon invitation). 14/11/17
- Research discussion. 23/01/17
- Personal invitation to seminars. 28/11/07
- Personal invitation to seminars. 26/11/07
- Personal invitation to seminars. 24/11/07
UNIZAR teaching activity
Teaching not UNIZAR
- Micromundo. Actividad Micromundo - Graduado en Veterinaria. Universidad de Zaragoza. 15/09/2019 - 30/06/2020
- Bacteria interactions. Bachelor in Biology. Utrecht University. 01/12/2017 - 20/03/2018
- Biogenesis of outer membrane and homeostasis. Master in Molecular and Cellular Life Sciences. Utrecht University. 20/03/2017 - 21/03/2017
- Membrane biogenesis and homeostasis (block iii). Master in Molecular and Cellular Life Sciences. Utrecht University. 15/09/2015 - 30/05/2016
- Academic research proposal. Bachelor in Biology. Utrecht University. 15/09/2014 - 15/02/2015
- Academic research proposal. Bachelor in Biology. Utrecht University. 15/09/2013 - 15/02/2014
- Academic research proposal. Bachelor in Biology. Utrecht University. 15/07/2012 - 15/02/2013
- Academic research proposal. Bachelor in Biology. Utrecht University. 15/09/2011 - 01/02/2012
- Techniques in molecular biology. Bachelor in Biology. Utrecht University. 15/01/2010 - 15/07/2010
- Microbiología (microbiology). Bachelor in Pharmacy (Licenciatura). Universidad de Santiago de Compostela. 01/01/2004 - 01/01/2005
- Microbiología (microbiology). Bachelor in Pharmacy (Licenciatura). Universidad de Santiago de Compostela. 01/01/2003 - 01/01/2004
- Microbiología (microbiology). Bachelor in Pharmacy (Licenciatura). Universidad de Santiago de Compostela. 01/01/2002 - 01/01/2003
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