Perfil (CV) del personal docente investigador

Martin Rapun, Rafael
Departamento: Departamento de Química Orgánica
Área: Química Orgánica
Centro: Facultad de Ciencias

Instituto: INSTITUTO DE NANOCIENCIA Y MATERIALES DE ARAGÓN (INMA)

Tramos de investigación
  • Sexenio convenio CNEAI. 27/06/23
  • Sexenio convenio CNEAI. 03/05/22
  • Sexenio convenio CNEAI. 06/07/21
  • Agencia de Calidad y Prospectiva Universitaria de Aragón (ACPUA). 22/08/19. (2)
Categoría profesional: Prof. Titular Univ.
Correo electrónico: rmartin@unizar.es
ORCID: 0000-0003-0702-8260

Líneas de investigación
  • Química orgánica
  • Nanoestructuras
  • Química orgánica supramolecular

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Artículos

  • Pamplona, Regina; González-Lana, Sandra; Romero, Pilar; Ochoa, Ignacio; Martín-Rapún, Rafael; Sánchez-Somolinos, Carlos. The Mechanical and Biological Performance of Photopolymerized Gelatin-Based Hydrogels as a Function of the Reaction Media. MACROMOLECULAR BIOSCIENCE. 2023. DOI: 10.1002/mabi.202300227

  • Bhandari, M.; Soria-Carrera, H.; Wohlmann, J.; Knudsen Dal, N. J.; Martínez de la Fuente, J. ; Martín-Rapún, R.; Griffiths, G.; Fenaroli, F. Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish. BIOMATERIALS SCIENCE. 2023. DOI: 10.1039/d2bm01835g

  • Pamplona, Regina; González-Lana, Sandra; Romero, Pilar; Ochoa, Ignacio; Martín-Rapún, Rafael; Sánchez-Somolinos, Carlos. Tuning of Mechanical Properties in Photopolymerizable Gelatin-Based Hydrogels for In Vitro Cell Culture Systems. ACS APPLIED POLYMER MATERIALS. 2023. DOI: 10.1021/acsapm.2c01980

  • Soria-Carrera, Héctor; Atrián-Blasco, Elena; Martín-Rapún, Rafael; Mitchell, Scott G. Polyoxometalate–peptide hybrid materials: from structure–property relationships to applications. CHEMICAL SCIENCE. 2022. DOI: 10.1039/d2sc05105b

  • Enderle, A. G.; Franco-Castillo, I.; Atrián-Blasco, E.; Martín-Rapún, R.; Lizarraga, L.; Culzoni, M. J.; Bollini, M.; de la Fuente, J. M.; Silva, F.; Streb, C.; Mitchell, S. G. Hybrid Antimicrobial Films Containing a Polyoxometalate-Ionic Liquid. ACS APPLIED POLYMER MATERIALS. 2022. DOI: 10.1021/acsapm.2c00110

  • Soria-Carrera, H.; Atrián-Blasco, E.; de la Fuente, J. M.; Mitchell, S. G.; Martín-Rapún, R. Polyoxometalate-polypeptide nanoassemblies as peroxidase surrogates with antibiofilm properties. NANOSCALE. 2022. DOI: 10.1039/d1nr08223j

  • Barbir R.; Ramírez Jiménez R.; Martín-Rapún R.; Strasser V.; Domazet Jurašin D.; Dabelic S.; Martínez de la Fuente J.; Vinkovic Vrcek I. Interaction of Differently Sized, Shaped, and Functionalized Silver and Gold Nanoparticles with Glycosylated versus Nonglycosylated Transferrin. ACS APPLIED MATERIALS & INTERFACES. 2021. DOI: 10.1021/acsami.1c04063

  • Soria-Carrera, H.; Franco-Castillo, I.; Romero, P.; Martin, S.; de la Fuente, J.M.; Mitchell, S.G.; Martin-Rapun, R. On-POM Ring-Opening Polymerisation of N-Carboxyanhydrides. ANGEWANDTE CHEMIE (INTERNATIONAL ED.). 2021. DOI: 10.1002/anie.202013563

  • Mabesoone, M.F.J.; Kardas, S.; Soria-Carrera, H.; Barbera, J.; Martinez de la Fuente, J.; Palmans, A.R.A.; Fossepre, M.; Surin, M.; Martin-Rapun, R. Competitive hydrogen bonding in supramolecular polymerizations of tribenzylbenzene-1, 3, 5-tricarboxamides. MOLECULAR SYSTEMS DESIGN & ENGINEERING. 2020. DOI: 10.1039/d0me00030b

  • Ramírez Jiménez, Rafael; Artiga, Álvaro; Mitchell, Scott G.; Martín Rapún, Rafael; de la Fuente, Jesús M. Surfactant-free synthesis and scalable purification of triangular gold nanoprisms with low non-specific cellular uptake. NANOMATERIALS. 2020. DOI: 10.3390/nano10030539

  • Baranyai, Z.; Soria-Carrera, H.; Alleva, M.; Millan-Placer, A.C.; Lucia, A.; Martin-Rapun, R.; Ainsa, J.A.; de la Fuente, J.M. Nanotechnology-Based Targeted Drug Delivery: An Emerging Tool to Overcome Tuberculosis. ADVANCED THERAPEUTICS. 2020. DOI: 10.1002/adtp.202000113

  • Soria-Carrera, H.; Lucía, A.; de Matteis, L.; Aínsa, J.A.; de la Fuente, J.M.; Martín-Rapún, R. Polypeptidic Micelles Stabilized with Sodium Alginate Enhance the Activity of Encapsulated Bedaquiline. MACROMOLECULAR BIOSCIENCE. 2019. DOI: 10.1002/mabi.201800397

  • de Matteis, L.; Martin-Rapun, R.; de la Fuente, J.M. Nanotechnology in Personalized Medicine: A Promising Tool for Alzheimer's Disease Treatment. CURRENT MEDICINAL CHEMISTRY. 2018. DOI: 10.2174/0929867324666171012112026

  • Martín-Rapún, R.; de Matteis, L.; Ambrosone, A.; García-Embid, S.; Gutiérrez, L.; de la Fuente, J.M. Targeted nanoparticles for the treatment of Alzheimer’s disease. CURRENT PHARMACEUTICAL DESIGN. 2017. DOI: 10.2174/1381612822666161226151011

  • Martín-Rapún, R.;Cano, M.;Mckenna, M.;Serrano, J. L.;Marcos, M. Side-on nematic liquid crystal dendrimers based on PAMAM and PPI as dendritic scaffolds: Synthesis and characterization. MACROMOLECULAR CHEMISTRY AND PHYSICS. 2015. DOI: 10.1002/macp.201400598

  • Cassani, Carlo; Martín-Rapún, Rafael; Arceo, Elena; Bravo, Fernando; Melchiorre, Paolo. Synthesis of 9-amino(9-deoxy)epi cinchona alkaloids, general chiral organocatalysts for the stereoselective functionalization of carbonyl compounds. NATURE PROTOCOLS. 2013. DOI: 10.1038/nprot.2012.155

  • Martín-Rapún, R.; Sayalero, S.; Pericàs, Ma. Asymmetric anti-Mannich reactions in continuous flow. GREEN CHEMISTRY. 2013. DOI: 10.1039/C3GC41444B

  • Gimeno,N.;Martín-Rapún,R.;Rodríguez-Conde,S.;Serrano,J. L.;Folcia,C. L.;Pericás,M. A.;Ros,M. B. "Click chemistry" as a versatile route to synthesize and modulate bent-core liquid crystalline materials. JOURNAL OF MATERIALS CHEMISTRY. 2012. DOI: 10.1039/c2jm33612j

  • Van Houtem, Mhcj.; Benaskar, F.; Fitié, Cfc.; Martín-Rapún, R.; Vekemans, Jajm.; Meijer, Ew. Helical self-assembly and co-assembly of fluorinated, preorganized discotics. ORGANIC & BIOMOLECULAR CHEMISTRY. 2012. DOI: 10.1039/C2OB25385B

  • Cambeiro, Xc.; Martín-Rapún, R.; Miranda, Po.; Sayalero, S.; Alza, E.; Llanes, P.; Pericàs, Ma. Continuous-flow enantioselective alpha-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY. 2011. DOI: 10.3762/bjoc.7.172

  • Alza, E.; Sayalero, S.; Cambeiro, Xc.; Martín-Rapún, R.; Miranda, Po.; Pericàs, Ma. Catalytic batch and continuous production of enantiopure cyclohexane derivatives with polymer-supported diarylprolinol silyl ethers. SYNLETT. 2011. DOI: 10.1055/s-0030-1259528

  • Martín-Rapún, R.; Fan, Xy.; Sayalero, S.; Bahramnejad, M.; Cuevas, F.; Pericàs, Ma. Highly Active Organocatalysts for Asymmetric anti-Mannich Reactions. CHEMISTRY - A EUROPEAN JOURNAL. 2011. DOI: 10.1002/chem.201101513

  • Metzroth, Thorsten; Hoffmann, Anke; Martín-Rapún, Rafael; Smulders, Maarten, M.J.; Pieterse, Koen; Palmans, Anja R.A.; Vekemans, Jef A.J.M.; Meijer, E.W.; Spiess, Hans W.; Gauss, Jürgen. Unravelling the fine structure of stacked bipyridine diamine-derived C3-discotics as determined by X-ray diffraction, quantum-chemical calculations, Fast-MAS NMR and CD spectroscopy. CHEMICAL SCIENCE. 2011. DOI: 10.1039/C0SC00292E

  • Stals, Pjm.; Everts, Jc.; de Bruijn, R.; Filot, Iaw.; Smulders, Mmj.; Martín-Rapún, R.; Pidko, Ea.; de Greef, Ta.; Palmans, Ara.; Meijer,E. W. Dynamic supramolecular polymers based on benzene-1,3,5-tricarboxamides: the influence of amide connectivity on aggregate stability and amplification of chirality. CHEMISTRY - A EUROPEAN JOURNAL. 2010. DOI: 10.1002/chem.200902635

  • González-Rodríguez, D.; Janssen, Pga.; Martín-Rapún, R.; de Cat, I.; de Feyter, S.; Schenning, Aphj.; Meijer, Ew. Persistent, well-defined, monodisperse, pi-conjugated organic nanoparticles via G-quadruplex self-assembly. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2010. DOI: 10.1021/ja908537k

  • Van Houtem, Mhcj.; Martín-Rapún, R.; Vekemans, Jajm.; Meijer, Ew. Desymmetrization of 3,3'-Bis(acylamino)-2,2'-bipyridine-based discotics: the high fidelity of their self-assembly behavior in the liquid-crystalline state and in solution. CHEMISTRY - A EUROPEAN JOURNAL. 2010. DOI: 10.1002/chem.200902416

  • Stals. Pjm.; Smulders, Mmj.; Martín-Rapún, R.; Palmans, Ara.; Meijer, Ew. Asymmetrically substituted benzene-1,3,5-tricarboxamides: Self-assembly and odd-even effects in the solid state and in dilute solution. CHEMISTRY - A EUROPEAN JOURNAL. 2009. DOI: 10.1002/chem.200802196

  • Martín-Rapún, R.; Byelov, D.; Palmans, Ara.; de Jeu, Wh.; Meijer, Ew. Lyomesophases of C3-Symmetrical Bipyridine-Based Discs in Alkanes: An X-ray Diffraction Study. LANGMUIR. 2009. DOI: 10.1021/la9003017

  • Stals, Patrick J. M.; Havernan, Jan F.; Martín-Rapún, Rafael; Fitié, Carel F. C.; Palmans, Anja R. A.; Meijer, E.W. The influence of oligo (ethylene glycol) side chains on the self-assembly of benzene-1,3,5-tricarboxamides in the solid state and in solution. JOURNAL OF MATERIALS CHEMISTRY. 2009. DOI: 10.1039/B816418E

  • Nielsen, Cb.; Veldman, D.; Martín-Rapún, R.; Janssen, Raj. Copolymers of Polyethylene and Perylenediimides through Ring-Opening Metathesis Polymerization. MACROMOLECULES. 2008. DOI: 10.1021/ma702350r

  • Van Den Hout, Kp.; Martín-Rapún, R.; Vekemans, Jajm.; Meijer, Ew. Tuning the Stacking Properties of C3-Symmetrical Molecules by Modifying a Dipeptide Motif. CHEMISTRY - A EUROPEAN JOURNAL. 2007. DOI: 10.1002/chem.200700630

  • Martin-Rapun, R.; Marcos,M.; Omena,A.; Serrano,J. L.; de Givenchy,E. T.; Guittard,F. Liquid Crystalline Semifluorinated Ionic Dendrimers. LIQUID CRYSTALS. 2007. DOI: 10.1080/02678290601171279

  • Marcos, M.;Martin-Rapun,R.;Omenat,A.;Serrano,J. L. Highly Congested Liquid Crystal Structures: Dendrimers, Dendrons, Dendronized and Hyperbranched Polymers. CHEMICAL SOCIETY REVIEWS. 2007

  • Marcos, M.; Martín-Rapún, R.; Omenat, A.; Barberá, J.; Serrano, Jl. Ionic Liquid Crystal Dendrimers with Mono-, Di- and Tri-substituted Benzoic Acids. CHEMISTRY OF MATERIALS. 2006. DOI: 10.1021/cm051677u

  • Marcos,M.;Martin-Rapun,R.;Omenat,A.;Barbera,J.;Serrano,J. L. Ionic liquid crystal dendrimers with mono-, di- and trisubstituted benzoic acids. CHEMISTRY OF MATERIALS. 2006

  • Rueff, J.M;Barbera, J;Marcos, M;Omenat, A;Martin-Rapun, R;Donnio, B;Guillon, D;Serrano, J.L. PAMAM- and DAB-derived dendromesogens: The plastic supermolecules. CHEMISTRY OF MATERIALS. 2006

  • Marcos, M.; Martín-Rapún, R.; Serrano, Jl.; Sánchez-Ferrer, A. Liquid crystalline dendritic networks derived from poly(propylene imine) (PPI) dendrimers. MACROMOLECULAR RAPID COMMUNICATIONS. 2005. DOI: 10.1002/marc.200500443

  • Marcos, Mercedes;Martin Rapun, Rafael;Serrano, Jose Luis;Sanchez Ferrer, Antoni. Liquid crystalline dendritic networks derived from poly(propylene imine) (PPI) dendrimers. MACROMOLECULAR RAPID COMMUNICATIONS. 2005

  • Martin Rapun, Rafael;Marcos, Mercedes;Omenat, Ana;Barbera, Joaquin;Romero, Pilar;Serrano, Jose L. Ionic thermotropic liquid crystal dendrimers. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2005

  • Martín-Rapún, R.; Marcos, M.; Omenat, A.; Serrano, Jl.; Luckhurst, Gr.; Mainal, A. Poly(propyleneimine) liquid crystal codendrimers bearing laterally and terminally attached promesogenic units. CHEMISTRY OF MATERIALS. 2004. DOI: 10.1021/cm049191

  • Martin Rapun, Rafael;Marcos, Mercedes;Omenat, Ana;Serrano, Jose Luis;Luckhurst, Geoffrey R.;Mainal, Azizah. Poly(propyleneimine) liquid crystal codendrimers bearing laterally and terminally attached promesogenic groups. CHEMISTRY OF MATERIALS. 2004. DOI: 10.1021/cm049191l

  • Pastor, Laura;Barbera, Joaquin;Mckenna, Mark;Marcos, Mercedes;Martin Rapun, Rafael;Serrano, Jose Luis;Luckhurst, Geoffrey R.;Mainal, Azizah. End-on and side-on nematic liquid crystal dendrimers. MACROMOLECULES. 2004

  • Serrano, J. L.;Marcos, M.;Martin, R.;Gonzalez, M.;Barbera, J. Chiral Codendrimers Derived From Poly(Propyleneimine) Dendrimers (Dab). CHEMISTRY OF MATERIALS. 2003

  • Serrano, Jl.; Marcos, M.; Martín, R.; González, M.; Barberá, J. Chiral Codendrimers Derived fron Poly(propyleneimine) Dendrimers (DAB). CHEMISTRY OF MATERIALS. 2003. DOI: 10.1021/cm030250p



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