Inés García Rubio graduated in Physics at the University of Zaragoza in 1997. With a doctorate FPU fellowship, she continued her scientific training at the Institute of Material Science of Aragón (ICMA) under the supervision of professors Pablo Alonso and Jesús Martínez. In 2002, she obtained her Ph.D. and in 2003 she started working as a postdoctoral researcher at the Chemistry Department of ETH Zurich, in the laboratory of Prof. Arthur Schweiger. From 2005-2007 she worked in the group of Prof. Beat Meier and then in the group of Prof. Gunnar Jeschke, all at ETH Zurich, a world reference in the field of magnetic resonance. In 2009 she was promoted to senior researcher (oberassistentin). In 2011 she started collaborating as a lecturer in the Centro Universitario de la Defensa, where, in 2016 she got a position of Profesor Contratado Doctor. She is also adscribed to the University of Zaragoza, as a collaborator of the Department of Physics of Condensed Matter.
Her scientific activity is centered on the application of Electron Paramagnetic Resonance (EPR) to systems of biological, chemical and technological interest. Her work is internationally recognized in the field, as echoed by the citations of her papers. Her studies on the active site of metalloproteins, mainly hemeproteins, through the investigation of hyperfine interactions of the metal with magnetic nuclei in the environment have been particularly relevant. Additionally, she has expanded the knowledge in the field of magnetotactic bacteria, where her contributions have consolidated Ferromagnetic Resonance as one of the main tools to assess magnetic anisotropy of nanoparticle arrays. Her works on flexibility and molecular arrangement of macromolecules through mobility and distance determination between paramagnetic probes have also made relevant contributions to the field of structural biology. Now, she is the leader of a small research group. Alone, or in collaboration with colleagues, she has been the principal investigator of a number of scientific projects granted financial support from different sources. The impact of her work has consolidated her as a usual invited speaker in international scientific forums, and member of scientific committees (e.g. EUROMAR 2020). Her scientific capabilities and good communication skills have granted her an important network of national and international collaborators, and the participation in international programs (e.g. H2020). She regularly collaborates with scientific journals by peer-reviewing articles, and with foreign funding agencies by evaluating grant applications (Argentina, Croacia, etc).
Mother of two children born in 2010 and 2013, she is committed with scientific outreach programs and regularly participates in the European researchers’ night and the activities of March 11th to promote the contributions of women in science. She is also dedicated to teaching of undergraduate and postgraduate classes and to training the next generation of scientists. She has supervised numerous bachelor, one masters and 4 PhD thesis (1 completed, 3 in course). Since the beginning of 2019, she participates as a PI in a European consortium of 5 universities, other research centers and 3 private companies (PARACAT) that has obtained funding from the European Commission in the frame H2020 to create an excellence training program for 10 doctoral students across Europe. She has co-authored 3 book chapters and a total of 63 research papers in JCR journals, from which 37 are Q1. According to Google Scholar, her articles have achieved a total of 1406 citations with an average of 113 citations/year in the last five years. She has presented a total of 8 invited lectures in international scientific meetings. Her h-index is 22.
She has been awarded with 3 six-year-periods of research activity by ACPUA, the regional evaluation agency in Aragon, and 4 five-year-periods of teaching activity.
Artículos
- Famulari, Antonino; Correddu, Danilo; Di Nardo, Giovanna; Gilardi, Gianfranco; Mitrikas, George; Chiesa, Mario; García-Rubio, Inés. Heme spin distribution in the Substrate-Free and Inhibited Novel CYP116B5hd: A multifrequency hyperfine sublevel correlation (HYSCORE) study. MOLECULES. 2024. DOI: 10.3390/molecules29020518
- Jojoa-Sierra, Sindy D.; Jaramillo-Paez, Cesar; Serna-Galvis, Efraím A.; García-Rubio, Inés; Hidalgo, María C.; Navío, José A.; Ormad, María P.; Torres-Palma, Ricardo A.; Mosteo, Rosa. Levofloxacin Degradation, Antimicrobial Activity Decrease, and Potential for Water Disinfection Using Peroxydisulfate Activation by Ag/TiO2 under Sunlight. WATER (SWITZERLAND). 2024. DOI: 10.3390/w16172434
- Quimbaya-Ñañez, Carolina; Serna-Galvis, Efraím A.; Silva-Agredo, Javier; García-Rubio, Inés; Torres-Palma, Ricardo A.; Ávila-Torres, Yenny P. Improvement of the carbocatalytic degradation of pharmaceuticals in water by the use of ultrasound waves. WATER (SWITZERLAND). 2023. DOI: 10.3390/w15203679
- Famulari, A.; Correddu, D.; Nardo, G.D.; Gilardi, G.; Chiesa, M.; García-Rubio, I. CYP116B5hd, a self-sufficient P450 cytochrome: A dataset of its electronic and geometrical properties. DATA IN BRIEF. 2022. DOI: 10.1016/j.dib.2022.108195
- Gracia, Pablo; Polanco, David; Tarancón-Díez, Jorge; Serra, Ilenia; Bracci, Maruan; Oroz, Javier; Laurents, Douglas V.; García-Rubio, Inés; Cremades, Nunilo. Molecular mechanism for the synchronized electrostatic coacervation and co-aggregation of a-synuclein and tau. NATURE COMMUNICATIONS. 2022. DOI: 10.1038/s41467-022-32350-9
- Serra, I.; Schmidt, D.; Pfanzagl, V.; Mlynek, G.; Hofbauer, S.; Djinovic-Carugo, K.; Furtmüller, P. G.; García-Rubio, Inés; Van Doorslaer, S.; Obinger, C. Impact of the dynamics of the catalytic arginine on nitrite and chlorite binding by dimeric chlorite dismutase. JOURNAL OF INORGANIC BIOCHEMISTRY. 2022. DOI: 10.1016/j.jinorgbio.2021.111689
- Serra, I; García Rubio, I.; Van Doorslaer, S. Pitfalls in Sample Preparation of Metalloproteins for Low-Temperature EPR: The Example of Alkaline Myoglobin. APPLIED MAGNETIC RESONANCE. 2022. DOI: 10.1007/s00723-021-01428-w
- Hidalgo, Nereida; Moreno, Juan José; García-Rubio, Inés; Campos, Jesús. Enhanced Dihydrogen Activation by Mononuclear Iridium(II) Compounds: A Mechanistic Study. ANGEWANDTE CHEMIE (INTERNATIONAL ED.). 2022. DOI: 10.1002/anie.202206831
- Arauzo, A.; Cabeza, J.A.; Fernández, I.; García-Álvarez, P.; García-Rubio, I.; Laglera-Gándara, C.J. Reactions of Late First-Row Transition Metal (Fe-Zn) Dichlorides with a PGeP Pincer Germylene. CHEMISTRY - A EUROPEAN JOURNAL. 2021. DOI: 10.1002/chem.202005289
- Jiang, X.; Payá-Tormo, L.; Coroian, D.; García-Rubio, I.; Castellanos-Rueda, R.; Eseverri, Á.; López-Torrejón, G.; Burén, S.; Rubio, L.M. Exploiting genetic diversity and gene synthesis to identify superior nitrogenase NifH protein variants to engineer N2-fixation in plants. COMMUNICATIONS BIOLOGY. 2021. DOI: 10.1038/s42003-020-01536-6
- García-Rubio, Inés. EPR of site-directed spin-labeled proteins: A powerful tool to study structural flexibility. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2020. DOI: 10.1016/j.abb.2020.108323
- Blattmann, Thomas M.; Lesniak, Barbara; García-Rubio, Inés; Charilaou, Michalis; Wessels, Martin; Eglinton, Timothy I.; Gehring, Andreas U. Ferromagnetic resonance of magnetite biominerals traces redox changes. EARTH AND PLANETARY SCIENCE LETTERS. 2020. DOI: 10.1016/j.epsl.2020.116400
- Bracci, M.; Van Doorslaer, S.; García-Rubio, I. EPR of Compound I: An Illustrated Revision of the Theoretical Model. APPLIED MAGNETIC RESONANCE. 2020. DOI: 10.1007/s00723-020-01278-y
- Manso, José A.; Gómez-Hernández, María; Carabias, Arturo; Alonso-García, Noelia; García-Rubio, Inés; Kreft, Maaike; Sonnenberg, Arnoud; Pereda, José M. de. Integrin a6ß4 recognition of a linear motif of bullous pemphigoid antigen BP230 controls its recruitment to hemidesmosomes. STRUCTURE. 2019. DOI: 10.1016/j.str.2019.03.016
- Bernal-Bayard, P.; Puerto-Galán, L.; Yruela, I.; García-Rubio, I.; Castell, C.; Ortega, J. M.; Alonso, P. J.; Roncel, M.; Martínez, J. I.; Hervás, M.; Navarro, J. A. The photosynthetic cytochrome c550 from the diatom Phaeodactylum tricornutum. PHOTOSYNTHESIS RESEARCH. 2017. DOI: 10.1007/s11120-016-0327-x
- Deuel, J.W.; Schaer, C.A.; Boretti; Opitz, L.; Garcia-Rubio, I.; Baek, J.H.; Spahn, D.R.; Buehler, P.W; Schaer, D.J. Hemoglobinuria-related acute kidney injury is driven by intrarenal oxidative reactions triggering a heme toxicity response. CELL DEATH & DISEASE. 2016. DOI: 10.1038/cddis.2015.392
- Schaer, Christian A.; Deuel, Jeremy W.; Schildknecht, Daniela; Mahmoudi, Leila; Garcia-Rubio, Ines; Owczarek, Catherine; Schauer, Stefan; Kissner, Reinhard; Banerjee, Uddyalok; Palmer, Andre F.; Spahn, Donat R.; Irwin, David C.; Vallelian, Florence; Buehler, Paul W.; Schaer, Dominik J. Haptoglobin preserves vascular nitric oxide signaling during hemolysis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016. DOI: 10.1164/rccm.201510-2058OC
- Fehr, N.; García-Rubio, I.; Jeschke, G.; Paulsen, H. Early folding events during light harvesting complex II assembly in vitro monitored by pulsed electron paramagnetic resonance. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS. 2016. DOI: 10.1016/j.bbabio.2016.04.004
- Koulialias, D.;García-Rubio, I.;Rahn-Lee, L.;Komeili, A.;Löffler, J. F.;Gehring, A. U.;Charilaou, M. Competitive and cooperative anisotropy in magnetic nanocrystal chains of magnetotactic bacteria. JOURNAL OF APPLIED PHYSICS. 2016. DOI: 10.1063/1.4961321
- Martínez,J. I.;Frago,S.;Lans,I.;Alonso,P. J.;García-Rubio,I.;Medina,M. Spin Densities in Flavin Analogs within a Flavoprotein. BIOPHYSICAL JOURNAL. 2016. DOI: 10.1016/j.bpj.2015.11.3525
- Manso, José Antonio; Garcia-Rubio, Ines; Gomez-Hernandez, Maria; Ortega, Esther; Buey, Ruben M.; Carballido, Ana María; Carabias, Arturo; Alonso-García, Noelia; de Pereda, José María. Purification and structural analysis of plectin and BPAG1e. METHODS IN ENZYMOLOGY. 2015. DOI: 10.1016/bs.mie.2015.05.002
- Lichtenberg, Crispin; Garcia-Rubio, Inés; Viciu, Liliana; Adelhardt, Mario; Meyer, Karsten; Jeschke, Gunnar; Grützmacher, Hansjörg. A Low-Valent Iron Imido Heterocubane Cluster: Reversible Electron Transfer and Catalysis of Selective C-C Couplings. ANGEWANDTE CHEMIE (INTERNATIONAL ED.). 2015. DOI: 10.1002/anie.201505668
- Vallelian, F.; Garcia-Rubio, I.; Puglia, M.; Kahraman, A.; Deuel, J. W.; Engelsberger, W. R.; Mason, R. P.; Buehler, P. W.; Schaer, D. J. Spin trapping combined with quantitative mass spectrometry defines free radical redistribution within the oxidized hemoglobin:haptoglobin complex. FREE RADICAL BIOLOGY AND MEDICINE. 2015. DOI: 10.1016/j.freeradbiomed.2015.04.023
- Alonso-García, N.; García-Rubio, I.; Manso, J.A.; Buey, R.M.; Urien, H.; Sonnenberg, A.; Jeschke, G.; de Pereda, J.M. Combination of X-ray crystallography, SAXS and DEER to obtain the structure of the FnIII-3,4 domains of integrin a6b4. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY. 2015. DOI: 10.1107/S1399004715002485
- Charilaou, M.; Rahn-Lee, L.; Kind, J.; García-Rubio, I.; Komeili, A.; Gehring, A. U. Anisotropy of bullet-shaped magnetite nanoparticles in the magnetotactic bacteria Desulfovibrio magneticus sp. strain RS-1. BIOPHYSICAL JOURNAL. 2015. DOI: 10.1016/j.bpj.2015.01.007
- Charilaou, M.; Kind, J.; García-Rubio, I.; Schüler, D.; Gehring, A. U. Magnetic anisotropy of non-interacting collinear nanocrystal-chains. APPLIED PHYSICS LETTERS. 2014. DOI: 10.1063/1.4869092
- Kielmann, U.; Jeschke, G.; García-Rubio, I. Structural characterization of polymer-clay nanocomposites prepared by co-precipitation using EPR techniques. MATERIALS. 2014. DOI: 10.3390/ma7021384
- Martínez Martínez, Jesús Ignacio; Alonso Gascón, Pablo Javier; García-Rubio, Inés; Medina Trullenque, Milagros. Methyl rotors in flavoproteins. PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2014. DOI: 10.1039/c4cp03115f
- Schaer, Ca; Deuel, Jw; Bittermann, Ag; Rubio, Ig; Schoedon, G; Spahn, Dr; Wepf, Ra; Vallelian, F; Schaer, Dj. Mechanisms of haptoglobin protection against hemoglobin peroxidation triggered endothelial damage. CELL DEATH AND DIFFERENTIATION. 2013. DOI: 10.1038/cdd.2013.113
- Kind, Jessica; García-Rubio, Inés; Charilaou, Michalis; Nowaczyk, N. R.; Löffler, J. F.; Gehring, Andreas. Domain-wall dynamics in 4C pyrrhotite at low temperature. GEOPHYSICAL JOURNAL INTERNATIONAL. 2013. DOI: 10.1093/gji/ggt262
- Gehring,A. U.;Kind,J.;Charilaou,M.;García-Rubio,I. S-band ferromagnetic resonance spectroscopy and the detection of magnetofossils. JOURNAL OF THE ROYAL SOCIETY INTERFACE. 2013. DOI: 10.1098/rsif.2012.0790
- Gehring, Andreas ; Charilaou, Michalis; García-Rubio, Inés. Oxidized magnetosomes in magnetotactic bacteria. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS. 2012. DOI: 10.1016/j.jmmm.2011.10.039
- Kind, Jessica; Van Randen, Ulrike; García-Rubio, Inés; Gehring, Andreas. Rock magnetic techniques complemented by ferromagnetic resonance spectroscopy to analise a sediment record. GEOPHYSICAL JOURNAL INTERNATIONAL. 2012. DOI: 10.1111/j.1365-246X.2012.05620.x
- Charilaou, Michalis; Sahu; Faivre, Damien; Fisher, Anna; Garcia-Rubio, Ines; Gehring, A. U. Evolution of magnetic anisotropy and thermal stability during nanocrystal-chain growth. APPLIED PHYSICS LETTERS. 2011. DOI: 10.1063/1.3658387
- Gehring, A.U.; Kind, J.; Charilaou, M.; Garcia Rubio, Ines. The detection of magnetotactic bacteria and magnetofossils by means of magnetic anisotropy. EARTH AND PLANETARY SCIENCE LETTERS. 2011. DOI: 10.1016/j.epsl.2011.06.024
- Alonso, P. J.;Arauzo, A. B.;García-Monforte, M. A.;García-Rubio, I.;Martín, A.;Menjón, B. ;Rillo, C. Synthesis, characterisation and magnetic properties of octahedral chromium(iii) compounds with six C-donor ligands. DALTON TRANSACTIONS. 2011. DOI: 10.1039/c0dt00891e
- Gehring, A. U.; Fischer, H.; Charilaou, M.; Garcia Rubio, Ines. Magnetic anisotropy, Verwey transition and the indentification of magnetofossils. GEOPHYSICAL JOURNAL INTERNATIONAL. 2011. DOI: 10.1111/j.1365-246X.2011.05175.x
- Garcia Rubio, Ines; Mitricas, George. Structure and spin density of ferric low-spin heme complexes determined with high-resolution ESEEM experiments at 35 GHz. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2010. DOI: 10.1007/s00775-010-0655-9
- Mastrogiacomo, Giovanni; Fisher, Hakon; Garcia Rubio, Ines; Gehring, Andreas. Ferromagnetic resonance spectroscopic response of magnetite chains in a biological matrix. JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS. 2010. DOI: 10.1016/j.jmmm.2009.10.035
- Faivre, Damien; Fischer, Anna; Garcia Rubio, Ines; Mastrogiacomo, Giovanni; Gehring, Andreas. Development of cellular magnetic dipoles in magnetotactic bacteria. BIOPHYSICAL JOURNAL. 2010. DOI: 10.1016/j.bpj.2010.05.034
- Tschaggelar, R.; Kasumaj, B.; Santangelo, M. G.; Forrer, J.; Leger, P.; Dube, H.; Diederich, F.; Harmer, J.; Schuhmann. R.; Garcia Rubio, Ines. Cryogenic 35 GHz pulse ENDOR probehead accommodating large sample sizes: Performance and applications. JOURNAL OF MAGNETIC RESONANCE. 2009. DOI: 10.1016/j.jmr.2009.06.007
- Moomaw, E. W.; Angerhofer, A.; Moussatche, P.; Ozarowski, A.; Garcia Rubio, Ines; Richards, N. G. J. Metal dependence of Oxalate Decarboxylase Activity. BIOCHEMISTRY. 2009. DOI: 10.1021/bi801856k
- Aldag, C.; Gromov, Igor; Garcia Rubio, Ines; Von Koenig, K.; Schlichting, I.; Jaun, B.; Hilvert, Donald. Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009. DOI: 10.1073/pnas.0810503106
- Kikkeri, R.; Garcia Rubio, Ines; Seeberger, P. H. Ru(II)-Carbohydrate dendrimers as photoinduced electron transfer lectin biosensors. CHEMICAL COMMUNICATIONS. 2009. DOI: 10.1039/B814146K
- Garcia-Rubio, Inés; Alonso, Pablo J.; Medina, Milagros; Martínez, Jesús I. HYSCORE AND ESEEM STUDY OF THE TWO COEXISTING FORMS OF THE HEMEPROTEIN CYTOCHROME C6 FROM ANABAENA PCC7119. BIOPHYSICAL JOURNAL. 2009
- García-Rubio, Inés; Alonso, Pablo J.; Medina, Milagros; Martínez, Jesús I. Hyperfine Correlation Spectroscopy and Electron Spin Echo Envelope Modulation Spectroscopy Study of the Two Coexisting Forms of the Hemeprotein Cytochrome c6 from Anabaena Pcc7119. BIOPHYSICAL JOURNAL. 2009. DOI: 10.1529/biophysj.108.133272
- Forrer, J.; Garcia Rubio, Ines; Schuhmam, R.; Tschaggelar, R.; Harmer, J. Cryogenic Q-band (35 GHz) probehead featuring large excitation microwave fields for pulse and continuous wave electron paramagnetic resonance spectroscopy: Performance and applications. JOURNAL OF MAGNETIC RESONANCE. 2008. DOI: 10.1016/j.jmr.2007.11.009
- Fittipaldi, M.; Garcia Rubio, Ines; Trandafir, F.; Gromov, I.; Schweiger, A.; Bouwen, A.; Van Doorslaer, S. A Multi-Frequency Pulse EPR and ENDOR Approach to Study Strongly Coupled Nuclei in Frozen Solutions of High-Spin Ferric Heme Proteins. JOURNAL OF PHYSICAL CHEMISTRY. B. 2008. DOI: 10.1021/jp709854x
- Garcia Rubio, Ines; Fittipaldi, M.; Trandafir, F.; Van Doorslaer, S. A multifrequency HYSCORE study of weakly coupled nuclei in frozen solutions of high-spin aquometmyoglobin. INORGANIC CHEMISTRY. 2008. DOI: 10.1021/ic8016886
- Angerhofer, A.; Moomaw, E.W.; Garcia Rubio, Ines; Ozarowski, A.; Krzystek, J.; Weber, R.T.; Richards, Nigel G. J. Multifrequency EPR studies on the Mn(II) centers of oxalate decarboxylase. JOURNAL OF PHYSICAL CHEMISTRY. B. 2007. DOI: 10.1021/jp0715326
- Garcia Rubio, Ines; Angerhofer, Alexander; Schweiger, Arthur. EPR and HYSCORE investigation of the electronic structure of the model complex Mn(imidazole)6: Exploring Mn(II)–imidazole binding using single crystals. JOURNAL OF MAGNETIC RESONANCE. 2007. DOI: 10.1016/j.jmr.2006.09.013
- Garcia Rubio, Ines; Braun, M.; Gromov, I.; Thony-Meyer, L.; Schweiger, Arthur. Axial coordination of heme in ferric CcmE chaperone characterized by EPR spectroscopy.. BIOPHYSICAL JOURNAL. 2007. DOI: 10.1529/biophysj.106.098277
- Alonso, P. J.;Martinez,J. I.;Garcia-Rubio,I. The Study of the Ground State Kramers Doublet of Low-Spin Heminic System Revisited - A Comprehensive Description of the EPR and Mossbauer Spectra. COORDINATION CHEMISTRY REVIEWS. 2007
- Garcia Rubio,Ines; Medina,Milagros; Cammack,Richard; Alonso,Pablo J.; Martinez,Jesus I. CW-EPR and ENDOR study of cytochrome c(6) from Anabaena PCC 7119. BIOPHYSICAL JOURNAL. 2006. DOI: 10.1529/biophysj.105.080358
- Calle, C.; Sreekanth, A.; Fedin, M. V.; Forrer, J.; Garcia Rubio, Ines; Gromov, I. A.; Hinderberger, D.; Kasumaj, B.; Léger, P.; Mancosu, B.; Mitrikas, G.; Santangelo, M. G.; Stoll, S.; Schweiger, A.; Tschaggelar, R.; Harmer, J. Pulse EPR Methods for Studying Chemical and Biological Samples Containing Transition Metals. HELVETICA CHIMICA ACTA. 2006. DOI: 10.1002/hlca.200690229
- Funhoff, E. G.; Bauer, U.; Garcia Rubio, Ines; Witholt, B.; Van Beilen, J. B. CYP153A6, a Soluble P450 Oxygenase Catalyzing Terminal-Alkane Hydroxylation. JOURNAL OF BACTERIOLOGY. 2006. DOI: 10.1128/JB.00286-06
- Iarrea, P;Moini, H;Rettori, D;Han, D;Martinez, J;Garcia, L;Fernandez Vizarra, E;Iturralde, M;Cadenas, E. Redox Activation of Mitochondrial Intermembrane Space Cu,Zn-Superoxide Dismutase. BIOCHEMICAL JOURNAL. 2005
- Braun, Martin; Garcia Rubio, Ines; Thoeny-Meyer, Linda. A heme tag for in vivo synthesis of artificial cytochromes. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2005. DOI: 10.1007/s00253-004-1804-2
- Yruela, I.;Garcia Rubio, I.;Roncel, M.;Martinez, J. I.;Ramiro, M. V.;Ortega, J. M.;Alonso, P. J.;Picorel, R. Detergent Effect on Cytochrome B(559) Electron Paramagnetic Resonance Signals in the Photosystem Ii Reaction Centre. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES. 2003
- Garcia-Rubio, I.;Martinez, J. I.;Picorel, R.;Yruela, I. L.;Alonso, P. J. Hyscore Spectroscopy in the Cytochrome B(559) of the Photosystem II Reaction Center. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2003
- Yruela, I.; Alfonso, M.; Garcia Rubio, I.; Martinez, J. I.; Picorel, R.; Alonso, P. J. Spin label electron paramagnetic resonance study in thylakoid membranes from a new herbicide-resistant D1 mutant from soybean cell cultures deficient in fatty acid desaturation. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2001. DOI: 10.1016/S0005-2736(01)00393-5
- Garcia-Rubio, I.;Pardo, J.A.;Merino, R.I.;Cases, R.;Orera, V.M. Concentration and temperature dependence of Nd**3** plus luminescence in LaGaO//3. JOURNAL OF LUMINESCENCE. 2000
- Garcia, I.;Peña, J. I.;Merino, R. I.;de la Fuente, G. F.;Orera, V. M. Growth of eutectic ZrO2(Y2O3)-Al2O3 fibres by laser floating zone technique. BOLETIN DE LA SOCIEDAD ESPANOLA DE CERAMICA Y VIDRIO. 1998
- García, I.;Peña, J. I.;Merino, R. I.;Orera, V.;de la Fuente, G.F. Crecimiento de fibras ZrO2(Y2O3)-Al2O3 eutécticas mediante la técnica de fusión zonal inducida por láser. BOLETIN DE LA SOCIEDAD ESPANOLA DE CERAMICA Y VIDRIO. 1998
Comunicaciones
Capítulos
- Pulsed ENDOR and ESEEM: Principles and Examples of Applications to Heme Proteins. Garcia Rubio, Ines. ENCYCLOPEDIA OF BIOPHYSICS. 2013
- Pulsed EPR: Principles and Examples of Applications to Heme Proteins. Garcia Rubio, Ines. ENCYCLOPEDIA OF BIOPHYSICS. 2013
Proyectos
- NAnotherapies DIagnostics by On-chip Spin resonance (NADIOS). 01/10/23 - 30/09/25
- Stimuli-responsive organic-inorganic hybrids to tackle the emerging threat of antimicrobial resistance (POM-deter). 01/10/23 - 30/09/25
- PID2021-127287NB-I00: Resonancia Paramagnética Electrónica para el estudio de Biomoléculas de Interés Médico y Tecnológico. 17/05/23 - 31/08/25
- Resonancia Paramagnética Electrónica para el estudio de biomoléculas de interés médico y tecnológico. 01/09/22 - 31/08/25
- LMP27_21: Enfermedades mitocondriales asociadas al mecanismo de importación y plegamiento oxidativo de proteínas en el espacio intermembrana de la mitocondria. Mecanismos moleculares y desarrollo de nuevas estrategias terapéuticas (EMPLOXPRO). 18/09/21 - 30/09/23
- UZCUD2020-BIO-01: Caracterización de las primeras interacciones entre moléculas de alfa-sinucleína que llevan a la formación de agregados tóxicos involucrados en la enfermedad de Párkinson. 01/10/20 - 30/09/21
- E35_20R: Biología Estructural. 01/01/20 - 31/12/22
- UZCUD2019-BIO-01: ESTUDIO DE LOS PRIMEROS CAMBIOS CONFORMACIONALES EN LA PROTEÍNA ALFA-SINUCLEÍNA IMPLICADOS EN LA ENFERMEDAD DE PARKINSON. 01/10/19 - 30/09/20
- PARACAT / Paramagnetic Species in Catalysis Research. A Unified Approach Towards Heterogeneous,
Homogeneous and Enzyme Catalysis (H2020 GA Number - 813209). 01/01/19 - 30/06/23
- UZCUD2017-BIO-02: ESTUDIO DE LA INTERACCIÓN DEL FACTOR DE INDUCCIÓN DE APOPTOSIS HUMANO (hAIF) CON SUS PAREJAS FISIOLÓGICAS MEDIANTE ESPECTROSCOPÍA DE EPR Y ESTUDIOS DE EXPRESIÓN CELULAR. 01/10/17 - 30/09/18
- GRUPO DE REFERENCIA BIOLOGÍA ESTRUCTURAL. 01/01/17 - 31/12/19
- UZCUD2016-BIO-02: ESTUDIO DE LA INTERACCIÓN DEL FACTOR DE INDUCCIÓN DE APOPTOSIS HUMANO (hAIF) CON SUS PAREJAS FISIOLÓGICAS MEDIANTE ESPECTROSCOPÍA DE EPR Y ESTUDIOS DE EXPRESIÓN CELULAR. 01/11/16 - 30/09/17
- CTQ2015-64486-R CATALIZADORES DE OXIGENACIÓN Y DE OXIDACIÓN DE AGUA. 01/01/16 - 31/12/19
- GRUPO CONSOLIDADO B18 BIOLOGÍA ESTRUCTURAL. 01/01/16 - 31/12/16
- Hacia futuras terapias de protección frente al daño oxidativo de la hemoglobina libre: ¿Cómo actúa la proteína haptoglobina?. 01/01/16 - 31/12/17
- UZ2015-CIE-07: APLICACIÓN DE TÉCNICAS DE RESONANCIA PARAMAGNÉTICA ELECTRÓNICA PARA EL DESARROLLO DE MATERIALES AVANZADOS BIOINSPIRADOS BASADOS EN COMPUESTOS DE CAPA ABIERTA. 01/10/15 - 30/09/16
- UZCUD2015-BIO-01: SEGUIMIENTO DE LOS CAMBIOS CONFORMACIONALES DEL DOMINIO APOPTÓTICO DEL FACTOR DE INDUCCIÓN DE APOPTOSIS HIMANO (hAIF) CON MARCAJE SELECTIVO DE ESPÍN Y ESPECTROSCOPIA DE EPR. 01/09/15 - 31/08/16
- GRUPO CONSOLIDADO B18 BIOLOGÍA ESTRUCTURAL. 01/01/15 - 31/12/15
- UZCUD2014-CIE-08. APLICACIÓN DE TÉCNICAS AVANZADAS DE RESONANCIA PARAMAGNÉTICA ELECTRÓNICA (EPR) PARA EL ESTUDIO DE ANÁLOGOS DEL ANILLO DE FLAVINA EN FLAVODOXINA: ELUCIDACIÓN DE LA ESTRUCTURA ELECTRÓNICA Y SU RELACIÓN CON LA FUNCIÓN DE FLAVOPROTEÍNAS. 01/10/14 - 30/06/15
- EPR spin labeling techniques for characterizing large-scale structural transitions of biomacromolecules. 01/10/12 - 30/09/14
- Probing the Oxidative Chemistry of Cytochome P450 with Selenocysteine-Containing Mutants. 01/04/11 - 31/03/14
- Assemblierung und Strukturdynamik des Haupt-Lichtsammlerkomplexes LHCII: Messung der Elektronen Paramagnetishen Resonanz (EPR). 01/10/10 - 30/03/14
- EPR probe techniques for characterizing structure and structural changes of biomolecules. 01/10/10 - 30/09/12
- EPR probe techniques for structural characterization of synthetic and biological macromolecular systems. 01/10/08 - 30/09/10
- Electron Paramagnetic Resonance Methodology and its Applications in Chemistry and Biophysics. 01/04/06 - 31/03/08
- Pulse Electron Spin Resonance Methodology and its Application in Chemistry, Material Science and Biophysics. 01/04/04 - 31/03/06
- Pulse Electron Spin Resonance Methodology and its Application in Material Science and Biophysics. 01/04/02 - 31/03/04
- BQU2001-2520.VERSATILIDAD DEL ANILLO DE ISOALOXAZINA COMO CENTRO REDOX. IMPLICACIONES EN PROCESOS DE TRANSFERENCIA DE ELECTRONES ENTRE PROTEINAS. 28/12/01 - 27/12/04
Dirección de tesis
- Interrogating Peroxidase Intermediate Compound I: a Rapid Freeze Quench ¿ EPR approach
Estudio del Compuesto I de Peroxidasas: un Ensayo entre Congelación Rápida y EPR. Universidad de Zaragoza. Sobresaliente cum laude. 24/11/23
- Understanding the molecular basis of industrially relevant biocatalysts: an electron paramagnetic resonance investigation of chlorite dismutases. Universidad de Amberes. Sobresaliente cum laude. 18/10/23
- Structural studies of weakly ordered materials. ETH Zurich. Sobresaliente. 10/10/12
- Towards tuning P450 reactivity: Study of the oxidation cycle of CYP116B5 using H2O2. Universidad de Zaragoza. In progress.
Dirección de proyectos fin de grado
- VAMTAC. Estudio para la adaptación al combate urbano en ambiente convencional- neer pear adversary. Universidad de Zaragoza. Notable. 08/02/23
- Diseño de una cisterna de combustible táctica sobre barcaza del TOA de carga M-548. Universidad de Zaragoza. Notable. 08/02/23
- Implementación de Vehículo Terrestre no Tripulado en Sección Mecanizada de Zapadores. Universidad de Zaragoza. Notable. 21/03/22
- Estudio de la alimentación del CC LEO 2E para posibilitar la instrucción estática de torre.
. Universidad de Zaragoza. Notable. 23/02/22
- IMPLEMENTACIÓN DEL SISTEMA BMS EN LA PLATAFORMA BMR-VCZ
. Universidad de Zaragoza. Notable. 27/01/21
- Estudio de las motivaciones del personal para la solicitud de vacantes y destinos.
. Universidad de Zaragoza. Aprobado. 27/01/21
- ANÁLISIS DE LAS HERRAMIENTAS DE MANDO Y CONTROL Y SISTEMAS GPS EN LA SECCIÓN DE INFANTERÍA LIGERO-PROTEGIDA
. Universidad de Zaragoza. Sobresaliente. 23/01/20
- ACTUALIZACION DEL LOTE DE SECCION LIGERA DE INGENIEROS PARA MISIONES PARACAIDISTAS
. Universidad de Zaragoza. Aprobado. 21/01/20
- Valoración de vehículos terrestres no tripulados para su uso en la sección ligera de zapadores. Universidad de Zaragoza. Notable. 16/01/20
- Estudio de los cambios confomacionales del dominio apoptótico del Factor de Inducción de Apoptosis Humano (hAIF) con marcaje selectivo de espin y espectroscopía de EPR. Universidad de Zaragoza. Notable. 17/12/19
- Interacción del Factor de Inducción de Apoptosis Humano con sus parejas fisiológicas mediante estudios de espectroscopía EPR y marcaje selectivo de espín. Universidad de Zaragoza. Sobresaliente. 27/09/19
- Configuración y enlace de centrales VOIP en los puestos de mando de Brigada y su integración con otros sistemas de telefonía. Universidad de Zaragoza. Aprobado. 25/01/19
- ¿Misiles PAC-2 vs PAC-3: análisis, comparación e implementación de los misiles PAC-3 CRI y PAC-3 MSE en el grupo PATRIOT. Universidad de Zaragoza. Sobresaliente. 22/01/19
- PROCEDIMIENTO Y ADQUISICIÓN DE MEDIOS PARA LA CONSTRUCCIÓN DE UN PUESTO DE MANDO SUBTERRÁNEO. Universidad de Zaragoza. Notable. 06/06/18
- ESTABLECIMIENTO DE DISPOSITIVOS C-RAM PARA DEFENSA DE BASES EN OPERACIONES, CON LAS CAPACIDADES ACTUALES DE LAS UNIDADES DE ARTILLERÍA. Universidad de Zaragoza. Notable. 12/02/18
- Seguimiento de los cambios conformacionales del dominio apoptótico del Factor de Inducción de Apoptosis Humano (hAIF) con marcaje selectivo de espín y espectroscopía de EPR. Universidad de Zaragoza. Notable. 02/10/17
- IMPLANTACIÓN DEL SISTEMA TALOS EN LAS UNIDADES DE INFANTERÍA Y SU INTEGRACIÓN EN LA MALLA DE DATOS DEL FSE. Universidad de Zaragoza. Aprobado. 30/05/17
- PROPUESTA DE EMPLEO DE LA CONSOLA LINPRO EN UN GAAA. Universidad de Zaragoza. Aprobado. 23/05/17
- EMPLEO DEL SISTEMA DE TIRO TALOS EN EL PLANEAMIENTO Y EJECUCIÓN DE LOS APOYOS DE FUEGO DEL BIL Y SU INTEGRACIÓN CON LOS APOYOS DE FUEGO DE ACA. Universidad de Zaragoza. Aprobado. 06/06/16
Dirección de proyectos fin de master
- Investigation about the chemical environment of Fe(III)in hemeproteins with saturation recovery experiments. ETH Zurich. Sobresaliente. 15/06/06
- EPR study of the highly anisotropic Low-Spin (HALS) heme centers (PPIX, TPP)-Fe(MeIm)2. ETH Zurich. Matrícula de Honor. 17/03/05
Investigaciones anteriores
- Profesora Titular. Universidad de Zaragoza. 16/05/23 - 26/12/23
- Profesora Centro Universitario de la Defensa. Academia General Militar. 01/10/11 - 16/05/23
- Senior Assistant. ETH Zurich. 01/01/09 - 30/09/11
- Postdoctoral Researcher. ETH Zurich. 08/01/03 - 31/12/08
- Becario de proyecto europeo. Universidad de Zaragoza. 01/06/02 - 30/09/02
- Becario FPU (MEC). Instituto de Ciencia de Materiales de Aragón. 01/06/98 - 31/05/02
- Becario de iniciación a la investigación (MEC). Universidad de Zaragoza. 15/09/96 - 15/06/97
Participaciones en congresos
- XIIth Conference of the European Federation of EPR groups (EFEPR). Participativo - Póster. Heme Spin Distribution in the Substrate-Free and Inhibited Novel CYP116B5hd: A HYSCORE Study. Marsella. 08/09/24
- XIIth Conference of the European Federation of EPR groups (EFEPR). Organizativo - Comité científico y organizador. Marsella. 08/09/24
- ICPP-13 INTERNATIONAL CONFERENCE ON PORPHYRINS & PHTHALOCYANINES. Participativo - Ponencia invitada/ Keynote. Probing Hemeprotein Active Sites with Hyperfine Spectroscopy. Niagara falls. 23/06/24
- XIII Meeting of the GIRSE (Gruppo di Risonanza di Spin Elettronico) 2023. Participativo - Ponencia invitada/ Keynote. What EPR can tell us about hemeproteins. Bologna. 18/09/23
- 9th EFEPR EPR Summer School. Participativo - Ponencia invitada/ Keynote. Fundamentals of Pulse EPR. Ginebra. 03/09/23
- EPR 2023 International Conference on EPR Spectroscopy and Imaging of Biological Systems. Participativo - Ponencia invitada/ Keynote. What can EPR tell us about hemeproteins?. París. 22/05/23
- Electron Paramagnetic Resonance in Catalysis. Participativo - Ponencia oral (comunicación oral). EPR investigation of CYP116B5hd electronic and coordination environment. Athens. 19/09/22
- Electron Paramagnetic Resonance in Catalysis. Participativo - Ponencia oral (comunicación oral). Understanding the molecular basis of industrially relevant biocatalysts: an EPR investigation of chlorite dismutases. Athens. 19/09/22
- Electron Paramagnetic Resonance in Catalysis. Participativo - Ponencia oral (comunicación oral). From production to reactivity. A story about Compound I. Athens. 19/09/22
- Euromar 2020. Organizativo - Comité científico y organizador. Bilbao (zoom). 06/12/20
- IX INTERNATIONAL CONFERENCE BIFI 2020 “NEW CHALLENGES IN MOLECULAR BIOTECHNOLOGY”. Participativo - Ponencia oral (comunicación oral). Fast Kinetic Studies of Relevant Peroxidases Aimed at a Freeze-Quench EPR Spectroscopy. Zaragoza. 03/02/20
- IX INTERNATIONAL CONFERENCE BIFI 2020 “NEW CHALLENGES IN MOLECULAR BIOTECHNOLOGY”. Participativo - Ponencia oral (comunicación oral). EPR and Chemical Studies About a New Species of the CYP450 Family: the CYP116B5. Zaragoza. 03/02/20
- XIth EFEPR Conference Bratislava 2019. Participativo - Póster. 13C hyperfine coupling characterization of the flavin semiquinone by EPR techniques. Bratislava. 01/09/19
- II Workshop on Spectroscopy Techniques: Generalities and Applications (WST2019). Participativo - Ponencia invitada/ Keynote. Pulsed Electron Paramagnetic Resonance: Applications in Biology and Material Science. Barcelona. 01/04/19
- 51st Annual International Meeting of the ESR Spectroscopy Group of the Royal Society of Chemistry. Participativo - Ponencia invitada/ Keynote. Studying the structural changes of human Apoptosis Inducing Factor using spin labels. Londres. 08/04/18
- XVI Congreso de la Sociedad de Biofísica. Participativo - Póster. EPR spectroscopy as an electronic and structural tool to study photosynthetic cytochrome c550. Sevilla. 06/06/17
- Xth EFEPR Conference. Participativo - Ponencia invitada/ Keynote. Structural Information from Hyperfine Couplings in Iron Catalysts. Turín. 04/09/16
- Rocky Mountain Conference on Magnetic Resonance. Participativo - Ponencia invitada/ Keynote. What Hyperfine Couplings can tell you about the structure in Iron Catalysts. Breckenridge. 24/07/16
- VII International Conference BIFI 2016 on Molecular Recognition. Participativo - Póster. Studying the structural changes of human Apoptosis Inducing Factor using site-selective spin-labeling. Zaragoza. 01/02/16
- IXth Conference of European Federation of EPR Societies. Participativo - Ponencia oral (comunicación oral). Combination of SAXS, DEER and X-ray crystallography to obtain the structure of FnIII3,4 domains of integrin. Marseille. 11/09/14
- IXth EF-EPR conference. Participativo - Póster. Tunnelling reorientation of a methyl group of the flavin ring characterized by pulse ENDOR. Marsella. 07/09/14
- 18th International Symposium on Flavins and Flavoproteins. Participativo - Póster. Tunnelling reorientation of the C8 methyl group in the flavin ring of Anabaena flavodoxin characterized by Electron-Nuclear Double Resonance (ENDOR). Phetchaburi. 27/07/14
- The first Awaji Island Workshop on Electron Spin Science and Spin Technology. Participativo - Ponencia invitada/ Keynote. Magnetic Anisotropy in Magnetotactic Bacteria Studied by Ferromagnetic Resonance. Awaji Island. 16/06/13
- 22nd IUBMB & 37th FEBS Congress of the Spanish Society of Biochemistry and Molecular Biology (SEBBM). Participativo - Otros. Structure of the second pair of fibronectin type III repeats of the integrin ß4 subunit. Sevilla. 04/12/12
- Current Trends in Nanoscopic and Mesoscopic Magnetism. Participativo - Ponencia invitada/ Keynote. Magnetic Anisotropy of 1D arrangements of Magnetic Nanoparticles. Ouranopolis. 12/06/12
- Euromar. Participativo - Ponencia invitada/ Keynote. Magnetic Resonance Studies on Magnetotactic Bacteria. Frankfurt. 22/08/11
- 42nd Annual International Meeting of the Electron Spin Resonance Group of the Royal Society of Chemistry. Participativo - Ponencia invitada/ Keynote. Tuning redox activity by replacing the proximal heme ligand in cytochrome P450cam with selenocysteine. Norwich. 19/04/09
- International COST Meeting ( 4th Joint Group and 5th Management Meeting). Participativo - Ponencia oral (comunicación oral). Advanced EPR techniques applied to the study of metmyoglobin, a model for high-spin ferric heme proteins in frozen solution. Siena. 24/09/08
- 35TH ANNUAL INTERNATIONAL MEETING ESR GROUP RSC "ADVANCED TECHNIQUES AND APPLICATIONS OF EPR". Participativo - Ponencia oral (comunicación oral). EPR AND ESSEM STUDIES OF LOW SPIN FERRIHEME CENTRES AND HEME PROTEINS. Aberdeen. 07/04/02
Comités
- Comité infraestructura MOSBRI. MOSBRI. 07/03/23
- Miembro del Comité Científico de Euromar 2020. EUROMAR. 08/08/19 - 31/07/20
Organizaciones de actividades de I+D+i
- Spectroscopic and Computational Methods towards Molecular Structure and Reactivity. 19/07/21 - 24/07/21
- Introduction to the Life Cycle Assessment methodology. 02/09/20 - 04/09/20
Evaluaciones en artículos I+D+i
- Participación en tribunales. No existe. España. 01/03/16 - 31/01/23
Otros méritos
- Spectroscopic and Computational Methods towards Molecular Structure and Reactivity. Curso extraordinario UNIZAR y curso CECAM. 19/07/21
- 1st PARACAT Summer School, Antwerp, Belgium. Full 6-day program (attendants will, when successful, be given a diploma - 4 ECTS)
Impartir clases de:
- Workshop: 'Theory and practice of EPR simulations'
- Lecture: 'CW-EPR examples in biocatalysis and biochemistry'. 14/07/19
- Nuevos Retos en Biología Molecular: las proteínas dúctiles y sus aplicaciones. - Análisis Estructural de IDPs mediante EPR: ventajas y limitaciones (1,5 h)
- Casos prácticos en el análisis de IDPs e IDRs por RMN y EPR (2 h). 11/07/18
UNIZAR teaching of the last six courses
- Física cuántica I. Graduado en Física. During academic year 2023-24
- Física cuántica I. Programa conjunto en Física-Matemáticas (FisMat). During academic year 2023-24
- Termodinámica. Graduado en Física. During academic year 2023-24
- Física II. Graduado en Ingeniería de Organización Industrial. During academic year 2022-23
- Física I. Graduado en Ingeniería de Organización Industrial. From the 2019-20 course to the 2021-22 course
Docencia no UNIZAR
- Quantum mechanics. Bachelors in Chemistry. ETH Zurich. 02/02/2009 - 15/06/2009
- Practicum spectroscopy. Bachelors in Chemistry and bachelors in Interdisciplinary Sciences. ETH Zurich. 01/10/2007 - 25/01/2010
- Advanced practicum of physical chemistry. Masters of Chemistry and Interdisciplinary Sciences. ETH Zurich. 02/04/2007 - 03/07/2011
- Undergraduate laboratory: part I. Bachelors in Chemistry. ETH Zurich. 04/04/2005 - 07/07/2006
- Physical chemistry part vii: signal acquisition and analysis. Masters of Chemistry. ETH Zurich. 11/10/2004 - 28/02/2006
- Physical chemistry part viii: pulse epr. Masters of Chemistry. ETH Zurich. 05/04/2004 - 05/07/2004
- Physical chemistry part vi: statistical thermodynamics. Masters of Chemistry. ETH Zurich. 12/10/2003 - 27/02/2004
- Chemistry for physicists. Bachelors in Physics. ETH Zurich. 01/04/2003 - 04/07/2003
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