Perfil (CV) del personal docente investigador

Latorre Duque, Eva
Departamento: Departamento de Bioquímica y Biología Molecular y Celular
Área: Biología Celular
Centro: Facultad de Ciencias

Research Institutes: INSTITUTO INVESTIGACIÓN SANITARIA DE ARAGÓN (IIS)
INSTITUTO AGROALIMENTARIO DE ARAGÓN (IA2)
Grupo: B31_23R: Inmunidad, Cáncer y Tratamientos Antiinflamatorios
Categoría profesional: Prof. Titular Univ.
Correo electrónico: evalatorre@unizar.es
Página web: https://evalatorre.weebly.com/

Titulaciones universitarias
  • Master en Iniciación a la Investigación en Ciencias Veterinarias, especialidad Ciencias básicas biomédicas. Facultad de Veterinaria. 2010
  • Licenciatura en Veterinaria. Universidad de Zaragoza. 2009

Doctorados
  • Ciencias Biomédicas y Biotecnológicas. Facultad de Veterinaria. 2015
 
             

Artículos

  • Layunta, E.; Mesonero, J.E.; Latorre, E. Guardians at the Gate: Immune System in Gastrointestinal Diseases. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024. DOI: 10.3390/ijms25115933

  • Pérez, Marina; Buey, Berta; Corral, Pilar; Giraldos, David; Latorre, Eva. Microbiota-derived short-chain fatty acids boost antitumoral natural killer cell activity. JOURNAL OF CLINICAL MEDICINE. 2024. DOI: 10.3390/jcm13133885

  • Gómez-Soria, Isabel; Iguacel, Isabel; Cuenca-Zaldívar, Juan Nicolás; Aguilar-Latorre, Alejandra; Peralta-Marrupe, Patricia; Latorre, Eva; Calatayud, Estela. Cognitive stimulation and psychosocial results in older adults: A systematic review and meta-analysis. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2023. DOI: 10.1016/j.archger.2023.105114

  • Buey, Berta; Layunta, Elena; Latorre, Eva; Mesonero, Jose Emilio. Potential role of milk bioactive peptides on the serotonergic system and the gut-brain axis. INTERNATIONAL DAIRY JOURNAL. 2023. DOI: 10.1016/j.idairyj.2022.105534

  • Buey, Berta; Forcén, Ana; Grasa, Laura; Layunta, Elena; Mesonero, Jose Emilio; Latorre, Eva. Gut microbiota-derived short-chain fatty acids: novel regulators of intestinal serotonin transporter. LIFE. 2023. DOI: 10.3390/life13051085

  • Gómez-Soria, Isabel; Iguacel, Isabel; Aguilar-Latorre, Alejandra; Peralta-Marrupe, Patricia; Latorre, Eva; Cuenca Zaldívar, Juan Nicolás; Calatayud, Estela. Cognitive stimulation and cognitive results in older adults: A systematic review and meta-analysis. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2023. DOI: 10.1016/j.archger.2022.104807

  • Gómez-Soria, Isabel; Marin-Puyalto, Jorge; Peralta-Marrupe, Patricia; Latorre, Eva; Calatayud, Estela. Effects of multi-component non-pharmacological interventions on cognition in participants with mild cognitive impairment: A systematic review and meta-analysis. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2022. DOI: 10.1016/j.archger.2022.104751

  • Latorre, E.; Mesonero, J. E. Special Issue “Clinical Advances in Chronic Intestinal Diseases Treatment”. JOURNAL OF CLINICAL MEDICINE. 2022. DOI: 10.3390/jcm11051258

  • Akesolo, Olaia; Buey, Berta; Beltrán-Visiedo, Manuel; Giraldos, David; Marzo, Isabel; Latorre, Eva. Toll-like receptors: New targets for multiple myeloma treatment?. BIOCHEMICAL PHARMACOLOGY. 2022. DOI: 10.1016/j.bcp.2022.114992

  • Layunta, Elena; Latorre, Eva; Grasa, Laura; Arruebo, María Pilar; Buey, Berta; Alcalde, Ana I.; Mesonero, José E. Intestinal serotonergic system is modulated by Toll-like receptor 9. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2022. DOI: 10.1007/s13105-022-00897-2

  • Gómez-Soria, Isabel; Iguacel, Isabel; Aguilar-Latorre, Alejandra; Peralta-Marrupe, Patricia; Latorre, Eva; Cuenca Zaldívar, Juan Nicolás; Calatayud, Estela. Cognitive stimulation and cognitive results in older adults: a systematic review and meta-analysis. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2022

  • Calatayud, Estela; Lozano-Berges, Gabriel; Peralta-Marrupe, Patricia; Latorre, Eva; Gomez-Soria, Isabel. Job demands may determine cognitive and physical aging after retirement. JOURNAL OF APPLIED GERONTOLOGY. 2022. DOI: 10.1177/07334648221120080

  • Layunta, Elena; Buey, Berta; Mesonero, Jose Emilio; Latorre, Eva. Crosstalk between intestinal serotonergic system and pattern recognition receptors on microbiota-gut-brain axis. FRONTIERS IN ENDOCRINOLOGY. 2021. DOI: 10.3389/fendo.2021.748254

  • Gros, Mónica; Gros, Belén; Mesonero, José Emilio; Latorre, Eva. Neurotransmitter Dysfunction in Irritable Bowel Syndrome: Emerging Approaches for Management. JOURNAL OF CLINICAL MEDICINE. 2021. DOI: 10.3390/jcm10153429

  • Buey, Berta; Bellés, Andrea; Latorre, Eva; Abad, Inés; Pérez, María Dolores; Grasa, Laura; Mesonero, Jose Emilio; Sánchez, Lourdes. Comparative effect of bovine buttermilk, whey, and lactoferrin on the innate immunity receptors and oxidative status of intestinal epithelial cells. BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE. 2021. DOI: 10.1139/bcb-2020-0121

  • Gómez-Soria, I.; Peralta-Marrupe, P.; Calatayud-Sanz, E.; Latorre, E. Efficacy of cognitive intervention programs in amnesic mild cognitive impairment: A systematic review. ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2021. DOI: 10.1016/j.archger.2020.104332

  • Marsilio, I.; Caputi, V.; Latorre, E.; Cerantola, S.; Paquola, A.; Alcalde, A.I.; Mesonero, J.E.; O'mahony, S.M.; Bertazzo, A.; Giaroni, C.; Giron, M.C. Oxidized phospholipids affect small intestine neuromuscular transmission and serotonergic pathways in juvenile mice. NEUROGASTROENTEROLOGY AND MOTILITY. 2020. DOI: 10.1111/nmo.14036

  • Lye Jed; Latorre, Eva; Lee, Ben; Bandinelli, Stefania; Holley, Janet; Gutowski, Nicholas; Ferrucci, Luigi; Harries, Lorna W. Senescence-related alterations in GFAP(A), p14-ARF and Tau3 transcript expression are associated with cognitive decline in human peripheral blood. GEROSCIENCE. 2019

  • Lasheras, I; Seral, P; Latorre, E; Barroso, E; Gracia-García, P; Santabárbara, J. Microbiota and gut-brain axis dysfunction in autism spectrum disorder: Evidence for functional gastrointestinal disorders. ASIAN JOURNAL OF PSYCHIATRY. 2019. DOI: 10.1016/j.ajp.2019.101874

  • Latorre, Eva; Mesonero, Jose Emilio; Harries, Lorna W. Alternative splicing in serotonergic system: Implications in neuropsychiatric disorders. JOURNAL OF PSYCHOPHARMACOLOGY. 2019. DOI: 10.1177/0269881119856546

  • Galvis, Daniel; Walsh, Darren; Harries, Lorna W.; Latorre, Eva; Rankin, James. A dynamical systems model for the measurement of cellular senescence. JOURNAL OF THE ROYAL SOCIETY INTERFACE. 2019. DOI: 10.1098/rsif.2019.0311

  • Grasa, Laura; Abecia, Leticia; Peña-Cearra, Ainize; Robles, Sofía; Layunta, Elena; Latorre, Eva; Mesonero, José Emilio; Forcen, Raquel. TLR2 and TLR4 interact with sulfide system in the modulation of mouse colonic motility. NEUROGASTROENTEROLOGY AND MOTILITY. 2019. DOI: 10.1111/nmo.13648

  • Latorre, E;Ostler, El; Faragher, Rga; Harries Lw. FOXO1 and ETV6 genes may represent novel regulators of splicing factor expression in cellular senescence. FASEB JOURNAL. 2019. DOI: 10.1096/fj.201801154R

  • Layunta, E.; Latorre, E.; Forcen, R,; Grasa, L.; Plaza, M. A.; Arias, M.; Alcalde, A. I.; Mesonero, J. E. NOD1 downregulates intestinal serotonin transporter and interacts with other pattern recognition receptors. JOURNAL OF CELLULAR PHYSIOLOGY. 2018. DOI: 10.1002/jcp.26229

  • Latorre, E;Torregrossa, R, Wood Me; Whiteman M; Harries Lw. Mitochondria-targeted hydrogen sulfide attenuates endothelial senescence by selective induction of splicing factors HNRNPD and SRSF2. AGING. 2018. DOI: 10.18632/aging.101500

  • Layunta, E,; Latorre, E,; Forcén, R,; Grasa, L,; Castro, M,; Arias, M.A,; Alcalde, A.I,; Mesonero, J.E. NOD2 Modulates Serotonin Transporter and Interacts with TLR2 and TLR4 in Intestinal Epithelial Cells. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2018. DOI: 10.1159/000490218.

  • Latorre, Eva; Pilling, Luke C.; Lee, Benjamin P.; Bandinelli, Stefania;Melzer, David;Ferrucci, Luigi; Harries, V. The VEGFA165b isoform is dysregulated in senescent endothelial cells and may be associated with prevalent and incident coronary heart disease. CLINICAL SCIENCE. 2018. DOI: 10.1042/CS20171556

  • Latorre, E.; Layunta, E.; Grasa, L.; Pardo, J.; García, S.; Alcalde, A. I.; Mesonero, J. E. Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2018. DOI: 10.1177/2050640617727180

  • Jeynes, Jcg; Geraki, K; Jeynes, C; Zhaohong, M; Bettiol, Aa; Latorre, E; Harries, Lw; Soeller C. Nanoscale Properties of Human Telomeres Measured with a Dual Purpose X-Ray Fluorescence and Super Resolution Microscopy Gold Nanoparticle Probe. ACS NANO. 2017. DOI: 10.1021/acsnano.7b07064

  • Latorre, E; Birar, Vc; Sheerin, An; Jeynes, Jcc; Hooper, A; Dawe, Hr; Melzer, D; Cox, Ls; Faragher, Rga; Ostler, El; Harries Lw. Small molecule modulation of splicing factor expression is associated with rescue from cellular senescence. BMC CELL BIOLOGY. 2017. DOI: 10.1186/s12860-017-0147-7

  • Peralta, Patricia; Gascón Ana; Latorre, Eva. Occupational Therapy Prevents Cognitive Impairment on Long-Term Care Residents. PHYSICAL & OCCUPATIONAL THERAPY IN GERIATRICS. 2017. DOI: 10.1080/02703181.2017.1339757

  • Latorre, E; Harries Lw. Splicing regulatory factors, ageing and age-related disease AGEING RESEARCH REVIEWS. 2017. DOI: 10.1016/j.arr.2017.04.004

  • Latorre, E.; Layunta, E.; Grasa, L.; Castro, M.; Pardo, J.; Gomollón, F.; Alcalde, A.I.; Mesonero, J.E. Intestinal serotonin transporter inhibition by toll-like receptor 2 activation. A feedback modulation. PLOS ONE. 2016. DOI: 10.1371/journal.pone.0169303

  • Latorre, E.; Pradilla, A.; Chueca, B.; Pagán, R.; Layunta, E.; Alcalde, A. I.; Mesonero, J. E. Listeria monocytogenes Inhibits Serotonin Transporter in Human Intestinal Caco-2 Cells. MICROBIAL ECOLOGY. 2016. DOI: 10.1007/s00248-016-0809-6

  • Forcén, R.; Latorre, E.; Pardo, J.; Alcalde, A. I.; Murillo, M. D.; Grasa, L. Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors. EXPERIMENTAL PHYSIOLOGY. 2016. DOI: 10.1113/EP085668

  • Grasa, Laura; Abecia, Leticia; Forcén, Raquel; Castro, Marta; García de Jalón, José Antonio; Latorre, Eva; Alcalde, Ana Isabel; Murillo, Maria Divina Antibiotic-induced depletion of murine microbiota induces mild inflammation and changes in toll-like receptor patterns and intestinal motility. MICROBIAL ECOLOGY. 2015. DOI: 10.1007/s00248-015-0613-8

  • Forcén, Raquel; Latorre, Eva; Pardo, Julián; Alcalde, Ana Isabel; Murillo, María Divina; Grasa, Laura. Toll like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved. NEUROGASTROENTEROLOGY AND MOTILITY. 2015. DOI: 10.1111/nmo.12619

  • Latorre, Eva; Matheus, Nyurky; Layunta, Elena; Alcalde, Ana Isabel; Mesonero, José Emilio. IL-10 counteracts proinflammatory mediator evoked oxidative stress in Caco-2 cells.. MEDIATORS OF INFLAMMATION. 2014. DOI: 10.1155/2014/982639

  • Latorre, E.; Mendoza, C.; Layunta, E.; Alcalde, A.I.; Mesonero, J.E. TLR2, TLR3, and TLR4 activation specifically alters the oxidative status of intestinal epithelial cells. CELL STRESS & CHAPERONES. 2014. DOI: 10.1007/s12192-013-0461-8

  • Matheus, N.; Mendoza, C.; Latorre, E.; Castro, M.; Mesonero, J.; Alcalde, A.I. Papel de la serotonina en el estado oxidativo de lípidos y proteínas en células epiteliales intestinales. BOLETÍN MÉDICO DE POSTGRADO. 2014

  • Latorre E.; Alcalde A.I.; Mesonero J.E. Implicación del transportador de serotonina (SERT) en las patologías inflamatorias intestinales. FISIOLOGÍA. 2013

  • Latorre,E.;Mendoza,C.;Matheus,N.;Castro,M.;Grasa,L.;Mesonero,J. E.;Alcalde,A. I. IL-10 modulates serotonin transporter activity and molecular expression in intestinal epithelial cells. CYTOKINE. 2013. DOI: 10.1016/j.cyto.2013.01.012

  • Mendoza,C.;Matheus,N.;Latorre,E.;Castro,M.;Mesonero,J. E.;Alcalde,A. I. Toll-like receptor 3 activation affects serotonin transporter activity and expression in human enterocyte-like caco-2 cells. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2012. DOI: 10.1159/000339057

  • Mesonero, J.E.; Latorre, E.; Mendoza, C.; Matheus, N.; Alcalde, A.I. Papel del sistema serotoninérgico en la fisiopatología intestinal GACETA DE CIENCIAS VETERINARIAS. 2012

  • Mendoza, C.; Matheus, N.; Iceta, R.; Latorre, E.; Mesonero, J.E.; Alcalde, A.I. Efecto de la activación del TLR4 en la función y expresión molecular de SERT. ACTA CIENTÍFICA VENEZOLANA. 2011

  • Mendoza, C.; Matheus, N.; Latorre, E.; Iceta, R.; Mesonero, J.E.; Alcalde, A.I. Efecto de la activación de TLR5 sobre la actividad del transportador de serotonina intestinal. GACETA DE CIENCIAS VETERINARIAS. 2011

  • Matheus, N.; Mendoza, C.; Iceta, R.; Latorre, E.; Mesonero, J.E.; Alcalde, A.I. Inhibición de la recaptación de serotonina por efecto de tratamiento crónico con melatonina. ACTA CIENTÍFICA VENEZOLANA. 2011

  • E. Latorre, C. Mendoza, N. Matheus, R. Iceta, J.E. Mesonero, B. Gros, S. García, R. Vicente, F. Gomollón, A.I. Alcalde. Modulación del transportador de serotonina (SERT) a través de factores antiinflamatorios. ARCHIVOS DE LA FACULTAD DE MEDICINA DE ZARAGOZA. 2010

  • Matheus, N; Mendoza, C; Iceta, R; Latorre, E; Mesonero, J.E; Plaza, Ma; Arruebo, Mp; Murillo, D; Castro, M; Grasa, L; Alcalde, A.I. Melatonin effect on serotonin transporter in Caco-2 cells. GENES AND NUTRITION. 2010. DOI: 10.1007/s12263-010-0205-7

  • Matheus, N; Mendoza, C; Iceta, R; Latorre, E; Mesonero, Je; Alcalde, Ai. Inhibición de la recaptación de serotonina en procesos inflamatorios. ARCHIVOS DE LA FACULTAD DE MEDICINA DE ZARAGOZA. 2009

Comunicaciones

  • Latorre, Eva; Forcén, Ana; Buey, Berta; Grasa, Laura; Mesonero, José Emilio. Microbiota-derived short-chain fatty acids as modulators of intestinal serotonin transporter. FEBS OPENBIO. 2021. DOI: 10.1002/2211-5463.13206

  • Marsilio, I.; Caputi, V.; Cerantola, S.; Latorre Duque, E.; Paquola, A.; Pattarello, A.; Orso, G.; Mesonero, J.E.; Bertazzo, A.; Giron, M.C. Involvement of the serotonin pathway in ileal neruomotor dysfunction associated with TLR2 and TLR4 inhibition in juvenille mice. NEUROGASTROENTEROLOGY AND MOTILITY. 2017. DOI: 10.1111/nmo.13180

  • Latorre, E.; Layunta, E.; Castro M.; Grasa, L.; Pardo, J.; Mesonero, J.E.; Alcalde, A.I. Interleukin-10 expression is regulated by Toll-like receptors 2 and 4 in intestinal epithelium. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2014. DOI: 10.1177/2050640614548990

  • Latorre, E.; Layunta, E.; Gimeno, A.; Grasa, L.; Castro, M.; García, S.; Gros, B.; Plaza, M.A.; Mesonero, J,E.; Alcalde, A.I. TLR2, TLR3 and TLR4 activation induces cellular oxidative damage in Caco-2 cells. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2013

  • Latorre, E.; Layunta, E.; Gimeno, A.; Grasa, L.; Castro, M.; Pardo, J.; Plaza, M.A.; Mesonero, J.E.; Alcalde, A.I. Activation of TLR2 affects intestinal serotonin transporter expression. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2013. DOI: 10.1007/s13105-013-0258-3

  • Grasa, L.; Castro, M.; Latorre, E.; Layunta, E.; Gonzalo, S.; Gimeno, A.; Mesonero, J.E.; Arruebo, M.P.; Plaza, M.A.; Alcalde, A.I.; Murillo, M.D. Depletion of murine intestinal microbiota by antibiotics: effects on gut transit and Toll-like receptors expression. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2013. DOI: 10.1177/2050640613505034

  • Matheus, N.; Mendoza, C.; Latorre, E.; Iceta, R.; Mesonero, J.E.; Alcalde, A.I. Efecto de la adenosina sobre el estado oxidativo de las células epiteliales durante procesos inflamatorios intestinales. ACTA CIENTÍFICA VENEZOLANA. 2013

  • Plaza, M.A.; Gimeno, A.; Castro, M.; Martínez, L.F.; Latorre, E.; Grasa, L.;Alcalde, A.I.; Mesonero, J.E.; Arruebo, M.P.; Murillo, M.D. Involvement of COX-2 derived from cerebral perivascular macrophages in the early gastrointestinal motor disturbances induced by Lipopolysaccharide (LPS) in sheep. NEUROGASTROENTEROLOGY AND MOTILITY. 2012

  • Plaza, M.A.; Gimeno, A.; Castro, M.; Martínez, L.F.; Latorre, E.; Grasa, L.; Alcalde, A.I.; Mesonero, J.E.; Arruebo, M.P.; Murillo, M.D. Early gastrointestinal motor disturbances induced by Lipopolysaccharide (LPS) in sheep may be initiated through activation of COX-2 in pulmonary and hepatic macrophages. NEUROGASTROENTEROLOGY AND MOTILITY. 2012

  • Gimeno, A.; Castro, M.; Martínez, L.F.; Latorre, E.; Grasa, L.; Alcalde, A.I; Mesonero, J.E.; Murillo, M.D.; Arruebo, M.P.; Plaza, M.A. Role of COX-2 from brain perivascular macrophages in the initiation of gastrointestinal (GI) motor disturbances and fever induced by LPS in sheep. ACTA PHYSIOLOGICA. 2012

  • Grasa, L.; Murillo, M.D.; Alcalde, A.I.; Pardo, J.; Latorre, E.; Mesonero, J.E.; Arruebo, M.P.; Plaza, M.A.; Gonzalo, S. Role of Toll-like receptors 2 and 4 in the serotonin-induced responses in mouse ileum and colon. NEUROGASTROENTEROLOGY AND MOTILITY. 2012

  • Latorre, E.; Layunta, E.; Grasa, L.; Castro, M.; Gimeno, A.; Plaza, M.A.; García, S.; Gros, B.; Mesonero, J.E.; Alcalde, A.I. Interleukin-10 reverses the oxidative damage induced by serotonin and TNFa in human enterocyte-like Caco-2 cells. ACTA PHYSIOLOGICA. 2012

  • Latorre, E.; Mendoza, C.; Matheus, N.; Castro, M.; Grasa, L.; Gimeno, A.; Plaza, M.A.; Gomollón, F.; Mesonero, J.E.; Alcalde, A.I. TLR3 and TLR4 activation and pro-inflammatory factors induce oxidative damage in enterocyte-like Caco-2 cells. ACTA PHYSIOLOGICA. 2012



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