Perfil (CV) del personal docente investigador

Artículos

• Garcia-Bonete, María José.; Rajan, Anandi; Suriano, Francesco; Layunta, Elena. The underrated gut microbiota helminths, bacteriophages, fungi, and archaea. LIFE. 2023. DOI: 10.3390/life13081765
  
  
• Buey, Berta; Forcén, Ana; Grasa, Laura; Layunta, Elena; Mesonero, Jose Emilio; Latorre, Eva. Gut microbiota-derived short-chain fatty acids: novel regulators of intestinal serotonin transporter. LIFE. 2023. DOI: 10.3390/life13051085
  
  
• Buey, Berta; Layunta, Elena; Latorre, Eva; Mesonero, Jose Emilio. Potential role of milk bioactive peptides on the serotonergic system and the gut-brain axis. INTERNATIONAL DAIRY JOURNAL. 2023. DOI: 10.1016/j.idairyj.2022.105534
  
  
• Layunta, Elena; Latorre, Eva; Grasa, Laura; Arruebo, María Pilar; Buey, Berta; Alcalde, Ana I.; Mesonero, José E. Intestinal serotonergic system is modulated by Toll-like receptor 9. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2022. DOI: 10.1007/s13105-022-00897-2
  
  
• Layunta, E.; Forcén, R.; Grasa López, L. TLR2 and TLR4 Modulate Mouse Ileal Motility by the Interaction with Muscarinic and Nicotinic Receptors; 35681486. CELLS. 2022. DOI: 10.3390/cells11111791
  
  
• Layunta, Elena; Buey, Berta; Mesonero, Jose Emilio; Latorre, Eva. Crosstalk between intestinal serotonergic system and pattern recognition receptors on microbiota-gut-brain axis. FRONTIERS IN ENDOCRINOLOGY. 2021. DOI: 10.3389/fendo.2021.748254
  
  
• Layunta, E.; Jäverfelt, S.; Dolan, B.; Arike, L.; Pelaseyed, T. IL-22 promotes the formation of a MUC17 glycocalyx barrier in the postnatal small intestine during weaning. CELL REPORTS. 2021. DOI: 10.1016/j.celrep.2021.108757
  
  
• Santiago, L.; Castro, Marta; Sanz-Pamplona, Rebeca; Garzón, Marcela; Ramírez-Labrada A.; Tapia E.; Moreno V.; Layunta, E.; Gil-Gómez, G.; Garrido, M.; Peña R.; Lanuza, P.M.; Comas L.; Jaime-Sánchez, P.; Uranga-Murillo, I.; del Campo, R.; Pelegrín, P.; Camerer, E.; Martínez-Lostao, L.; Muñoz, G.; Uranga, J.A.; Alcalde, A.; Galvez, E.M.; Ferrández, A.; Bird, P.I.; Metkar, S.; Arias, M.A.; Pardo, J. Extracellular granzyme A promotes colorectal cancer development by enhancing gut inflammation. CELL REPORTS. 2020. DOI: 10.1016/j.celrep.2020.107847
  
  
• Layunta Hernández, Elena; Pastor Arroyo, Eva Maria; Kägi, Larissa; Thomas, Linto; Levi, Moshe; Hernando, Nati; Wagner, Carsten A Intestinal Response to Acute Intragastric and Intravenous Administration of Phosphate in Rats. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2019. DOI: 10.33594/000000058
  
  
• Layunta, E.; Jäverfelt, S.; Pelaseyed, T. Muc17 functional maturation and expression in intestine is age-dependent. FEBS OPENBIO. 2019. DOI: 10.1002/2211-5463.12675
  
  
• Grasa, Laura; Abecia, Leticia; Peña-Cearra, Ainize; Robles, Sofía; Layunta, Elena; Latorre, Eva; Mesonero, José Emilio; Forcen, Raquel. TLR2 and TLR4 interact with sulfide system in the modulation of mouse colonic motility. NEUROGASTROENTEROLOGY AND MOTILITY. 2019. DOI: 10.1111/nmo.13648
  
  
• Latorre, E.; Layunta, E.; Grasa, L.; Pardo, J.; García, S.; Alcalde, A. I.; Mesonero, J. E. Toll-like receptors 2 and 4 modulate intestinal IL-10 differently in ileum and colon. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2018. DOI: 10.1177/2050640617727180
  
  
• Layunta, E.; Latorre, E.; Forcen, R,; Grasa, L.; Plaza, M. A.; Arias, M.; Alcalde, A. I.; Mesonero, J. E. NOD1 downregulates intestinal serotonin transporter and interacts with other pattern recognition receptors. JOURNAL OF CELLULAR PHYSIOLOGY. 2018. DOI: 10.1002/jcp.26229
  
  
• Layunta, E,; Latorre, E,; Forcén, R,; Grasa, L,; Castro, M,; Arias, M.A,; Alcalde, A.I,; Mesonero, J.E. NOD2 Modulates Serotonin Transporter and Interacts with TLR2 and TLR4 in Intestinal Epithelial Cells. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY. 2018. DOI: 10.1159/000490218.
  
  
• Latorre, E.; Layunta, E.; Grasa, L.; Castro, M.; Pardo, J.; Gomollón, F.; Alcalde, A.I.; Mesonero, J.E. Intestinal serotonin transporter inhibition by toll-like receptor 2 activation. A feedback modulation. PLOS ONE. 2016. DOI: 10.1371/journal.pone.0169303
  
  
• Latorre, E.; Marsilio, I.; Caputi, V.; Layunta, E.; Cerantola, S.; Mesonero, J.E.; Giron, C. Effects of Toll-like receptors 2 and 4 inhibition on intestinal contractility and serotoninergic system of mouse enteric nervous system. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Latorre, E.; Layunta, E.; Mendoza, C.; Matheus, N.; García, S.; Gomollón, F.; Mesonero, J.E. Activation of Toll-like receptor 5 modulates the intestinal serotonin transporter in Caco-2 cells: comparative study with other Toll-like receptors. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Layunta, E.; Latorre, E.; Alcutén, R.; Castro, M.; Gros, B.; Vicente, R.; Arruebo, M.P.; Plaza, M.A.; Mesonero, J.E. Different intracellular pathways are involved in the modulation of the serotonin transporter by NODs activation in Caco-2 cells. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Layunta, E.; Latorre, E.; Forcén, R.; Grasa, L.; Pardo, J.; Castro, M.; Plaza, M.A.; Arruebo, M.P.; Mesonero, J.E. Toll-like receptor 9 modifies intestinal serotonergic system.. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2016. DOI: 10.1177/2050640616663689
  
  
• Layunta, E.; Latorre, E.; Mesonero, J.E. Role of the serotonin transporter in the pathophysiology intestinal. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Layunta, E.; Latorre, E.; Forcén, R.; Grasa, L.; Castro, M.; Pardo, J.; Mesonero J.E. Interrelationship between NOD and TLR receptors in the intestinal tract of mice. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Forcén, R.; Layunta, E.; Susunaga-Notario, A.C.; Mesonero, J.E.; Grasa, L. Antibiotic-induced depletion of microbiota induces changes in the motor response to serotonin in mouse ileum. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Latorre, E.; Pradilla, A.; Chueca, B.; Pagán, R.; Layunta, E.; Alcalde, A. I.; Mesonero, J. E. Listeria monocytogenes Inhibits Serotonin Transporter in Human Intestinal Caco-2 Cells. MICROBIAL ECOLOGY. 2016. DOI: 10.1007/s00248-016-0809-6
  
  
• Forcén, R.; Layunta, E.; Pardo, J.; Mesonero, J.E.; Grasa, L. Toll-like receptor 2 modulates the inhibitory motor response induced by hydrogen sulphide in mouse colon. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2016. DOI: 10.1177/2050640616663688
  
  
• Latorre, E.; Layunta, E.; Gimeno, A.; Grasa, L.; Castro, M.; García, S.; Gros, B.; Arruebo, M.P.; Alcalde, A.I.; Mesonero, J.E. Oxidative stress balance between pro- and anti-inflammatory factors in human intestinal epithelial cells. ACTA PHYSIOLOGICA. 2015. DOI: 10.1111/apha.12498
  
  
• Layunta, E.; Latorre, E.; Grasa, L.; Castro, M.; Pardo, J.; Gomollón, F.; Alcalde, A.I.; Mesonero, J.E. NOD1 and NOD2 interact with serotonin transporter and Toll-like receptors in intestinal epithelial cells. Analysis in intestinal tract from mice colitis model. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2015
  
  
• Latorre, E.; Pradilla, A.; Chueca, B.; Pagan, R.; Layunta, E.; Mesonero, J.E.; Alcalde, A.I. Listeria monocytogenes affects serotonin transporter activity and expression in human intestinal epithelial cells by TLR10 activation. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2015
  
  
• Layunta, E.; Latorre, E.; Gimeno, A.; Grasa, L.; Castro, M.; Plaza, M.A.; Pardo, J.; Gomollón, F.; Alcalde, A.I.; Mesonero, J.E. Toll-like receptor 9 activation affects intestinal serotonin transporter activity and expression in Caco-2 cells. ACTA PHYSIOLOGICA. 2015
  
  
• Nevado, R.; Forcén, R.; Layunta, E.; Murillo, M. D.; Grasa, L. Neomycin and bacitracin reduce the intestinal permeability in mice and increase the expression of some tight-junction proteins. REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS. 2015. DOI: 10.17235/reed.2015.3868/2015
  
  
• Latorre, E.; Mendoza, C.; Layunta, E.; Alcalde, A.I.; Mesonero, J.E. TLR2, TLR3, and TLR4 activation specifically alters the oxidative status of intestinal epithelial cells. CELL STRESS & CHAPERONES. 2014. DOI: 10.1007/s12192-013-0461-8
  
  
• Latorre, Eva; Matheus, Nyurky; Layunta, Elena; Alcalde, Ana Isabel; Mesonero, José Emilio. IL-10 counteracts proinflammatory mediator evoked oxidative stress in Caco-2 cells.. MEDIATORS OF INFLAMMATION. 2014. DOI: 10.1155/2014/982639
  
  

Comunicaciones

• Bueno, J.L.; Moreo, E.; Valero, M.S.; Santiago, L.; Arias, M.; Layunta, E.; Calvo, A.C.; Pardo, J.; Arruebo, M.P.; Plaza, M.A.; Castro, M. Role of granzyme a in the regulation of small intestinal motility in mice. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2016
  
  
• Layunta, E.; Latorre, E.; Grasa, L.; Castro, M.; Plaza, M.A.; Pardo, J.; Santiago, L.; Medina de Sánchez , F.; Martínez-Augustin, O.; Ocón, B.; Aranda, C.; Mesonero, J.E.; Alcalde, A.I. Expression of microbiota recognition receptors and intestinal serotoninergic system in two mouse models of colitis. ACTA PHYSIOLOGICA. 2015
  
  
• Latorre, E.; Layunta, E.; Castro M.; Grasa, L.; Pardo, J.; Mesonero, J.E.; Alcalde, A.I. Interleukin-10 expression is regulated by Toll-like receptors 2 and 4 in intestinal epithelium. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2014. DOI: 10.1177/2050640614548990
  
  
• Grasa, L.; Castro, M.; Latorre, E.; Layunta, E.; Gonzalo, S.; Gimeno, A.; Mesonero, J.E.; Arruebo, M.P.; Plaza, M.A.; Alcalde, A.I.; Murillo, M.D. Depletion of murine intestinal microbiota by antibiotics: effects on gut transit and Toll-like receptors expression. UNITED EUROPEAN GASTROENTEROLOGY JOURNAL. 2013. DOI: 10.1177/2050640613505034
  
  
• Latorre, E.; Layunta, E.; Gimeno, A.; Grasa, L.; Castro, M.; Pardo, J.; Plaza, M.A.; Mesonero, J.E.; Alcalde, A.I. Activation of TLR2 affects intestinal serotonin transporter expression. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2013. DOI: 10.1007/s13105-013-0258-3
  
  
• Latorre, E.; Layunta, E.; Gimeno, A.; Grasa, L.; Castro, M.; García, S.; Gros, B.; Plaza, M.A.; Mesonero, J,E.; Alcalde, A.I. TLR2, TLR3 and TLR4 activation induces cellular oxidative damage in Caco-2 cells. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY. 2013
  
  
• Latorre, E.; Layunta, E.; Grasa, L.; Castro, M.; Gimeno, A.; Plaza, M.A.; García, S.; Gros, B.; Mesonero, J.E.; Alcalde, A.I. Interleukin-10 reverses the oxidative damage induced by serotonin and TNFa in human enterocyte-like Caco-2 cells. ACTA PHYSIOLOGICA. 2012
  
  

Colaboraciones en ediciones de revista

• Life. 2075-1729. 01/09/22
  
  
• International Journal of Molecular Sciences. 1661-6596. 01/09/22
  
  

Proyectos

• A20_23R: Efecto del Procesado Tecnológico de los Alimentos en las Patologías Digestivas y Alérgicas” (ALIPAT). 01/01/23 - 31/12/25
  
  
• Defining functional role of membrane mucins in mucosal barrier of the intestine. 01/11/22 - 01/11/23
  
  
• MUC17 glycocalyx barrier modulation as a novel therapeutic strategy to restore the protective mucus in ulcerative colitis. 01/07/22 - 31/05/23
  
  
• Novel therapy for gastrointestinal infections in ulcerative colitis based in the reinforcement of the glycocalyx barrier and the preservation of the epithelial architecture in the intestines. 31/08/21 - 31/07/22
  
  
• New therapy in Crohn´s disease based in the enhancement of the intestinal glycocalyx barrier and the reinforcement of the microvilli structure. 01/08/20 - 31/07/21
  
  
• A20_20R: ALIPAT (Grupo De Investigación Sobre El Efecto Del Procesado Tecnológico De Los Alimentos En Las Patologías Digestivas Y Alérgicas). 01/01/20 - 31/12/22
  
  
• The role of transmembrane mucins in the protection of the host against gut bacteria. 01/06/19 - 01/06/20
  
  
• Transmembrane mucins as a key component in inflammatory bowel disease. 01/06/19 - 31/07/20
  
  
• GRUPO CONSOLIDADO B61 FISIOPATOLOGÍA GASTROINTESTINAL. 01/01/16 - 31/12/16
  
  
• GRUPO CONSOLIDADO B61 FISIOPATOLOGÍA GASTROINTESTINAL. 01/01/15 - 31/12/15
  
  
• GRUPO CONSOLIDADO B61 FISIOPATOLOGÍA GASTROINTESTINAL. 01/01/14 - 31/12/14
  
  

Contratos

• Investigador. 19/01/22 - 10/02/23
  
  
• Investigador Post-Doctoral. 19/01/20 - 18/01/22
  
  
• Wenner-Gren Foundations Fellowship. 18/01/19 - 17/01/20
  
  
• Wenner-Gren Foundations Fellowship. 18/01/18 - 17/01/19
  
  
• FISIOPATOLOGÍA GASTROINTESTINAL (PHYSIOGUT). 01/11/15 - 31/10/20
  
  
• IA2. 01/11/15 - 31/10/30
  
  
• FISIOPATÍA EN LAS ENFERMEDADES INFLAMATORIAS INTESTINALES CRÓNICAS. (DONACIÓN). 14/11/12 - 31/12/12
  
  

Estancias

• Estancia Post-Doctoral. Gotemburgo Suecia. 18/01/18 - 10/02/23
  
  
• Estancia internacional pre-doctoral. Zúrich. Suiza. 01/04/16 - 28/09/16
  
  

UNIZAR teaching activity

• Embriología y anatomía I. Graduado en Veterinaria. From the 2023-24 course to the 2024-25 course
  
  
• Embriología y anatomía II. Graduado en Veterinaria. From the 2023-24 course to the 2024-25 course
  
  
• Modelos de investigación de la enfermedad. Máster Universitario en Salud Global: Integración de la Salud Ambiental, Humana y Animal. From the 2023-24 course to the 2024-25 course
  
  
• Trabajo fin de grado. Graduado en Veterinaria. During academic year 2023-24
  
  
• Trabajo fin de grado. Graduado en Ciencia y Tecnología de los Alimentos. During academic year 2023-24
  
  
• Trabajo fin de máster. Máster Universitario en Biología Molecular y Celular. During academic year 2023-24
  
  
• Trabajo fin de máster. Máster Universitario en Salud Global: Integración de la Salud Ambiental, Humana y Animal. During academic year 2023-24
  
  
• Fisiología animal. Graduado en Veterinaria. During academic year 2021-22
  
  
• Modelos de investigación de la enfermedad. Máster Universitario en Salud Global: Integración de la Salud Ambiental, Humana y Animal. During academic year 2021-22
  
  
• Fisiología animal. Graduado en Veterinaria. From the 2014-15 course to the 2016-17 course
  
  
• Fisiología general y de la nutrición. Graduado en Ciencia y Tecnología de los Alimentos. During academic year 2015-16
  
  
• Fisiologia. Graduado en Biotecnología. During academic year 2014-15
  
  

Docencia no UNIZAR

• Basic science and early professional contact 1. Programme in Medicine. UNIVERSIDAD DE GOTEMBURGO. 01/09/2021 - 01/09/2022
  
  
• Molecular cell biology. Programme in Medicine. UNIVERSIDAD DE GOTEMBURGO. 01/09/2020 - 01/09/2021